In vivo quantification of pulmonary inflammation in relation to emphysema severity via partial volume corrected (18) F-FDG-PET using computer-assisted analysis of …

DA Torigian, V Dam, X Chen, B Saboury… - Hellenic journal of …, 2013 - europepmc.org
Our aim was to quantify the degree of pulmonary inflammation associated with centrilobular
emphysema using fluoro-18-2-fluoro-2-deoxy-D-glucose positron emission tomography …

Quantification of lung PET images: challenges and opportunities

DL Chen, J Cheriyan, ER Chilvers… - Journal of Nuclear …, 2017 - Soc Nuclear Med
Millions of people are affected by respiratory diseases, leading to a significant health burden
globally. Because of the current insufficient knowledge of the underlying mechanisms that …

Assessment of pulmonary neutrophilic inflammation in emphysema by quantitative positron emission tomography

DR Subramanian, L Jenkins, R Edgar… - American journal of …, 2012 - atsjournals.org
Rationale: Neutrophilic inflammation is understood to be of pathogenetic importance in
chronic obstructive pulmonary disease (COPD) and may be quantified using 18 …

The importance of correction for tissue fraction effects in lung PET: preliminary findings

T Lambrou, AM Groves, K Erlandsson… - European journal of …, 2011 - Springer
Purpose It has recently been recognized that PET/CT may play a role in diffuse parenchymal
lung disease. However, interpretation can be confounded due to the variability in lung …

[HTML][HTML] Quantitative analysis of dynamic 18F-FDG PET/CT for measurement of lung inflammation

C Coello, M Fisk, D Mohan, FJ Wilson, AP Brown… - EJNMMI research, 2017 - Springer
Background An inflammatory reaction in the airways and lung parenchyma, comprised
mainly of neutrophils and alveolar macrophages, is present in some patients with chronic …

PET measurement of regional lung density: 1

DP Schuster, GF Marklin, MA Mintun… - Journal of computer …, 1986 - journals.lww.com
Regional lung density (LD) and lung water (LW) measurements were made with positron
transmission and emission tomography (PET) in normal and edematous lung in supine dogs …

[HTML][HTML] Automatic delineation of functional lung volumes with 68Ga-ventilation/perfusion PET/CT

PY Le Roux, S Siva, J Callahan, Y Claudic, D Bourhis… - EJNMMI research, 2017 - Springer
Background Functional volumes computed from 68 Ga-ventilation/perfusion (V/Q) PET/CT,
which we have shown to correlate with pulmonary function test parameters (PFTs), have …

Comparison of static and dynamic 18F-FDG PET/CT for quantification of pulmonary inflammation in acute lung injury

A Braune, F Hofheinz, T Bluth, T Kiss… - Journal of Nuclear …, 2019 - Soc Nuclear Med
PET imaging with 18F-FDG followed by mathematic modeling of the pulmonary uptake rate
(Ki) is the gold standard for assessment of pulmonary inflammation in experimental studies …

Improved correction for the tissue fraction effect in lung PET/CT imaging

BF Holman, V Cuplov, L Millner… - Physics in Medicine …, 2015 - iopscience.iop.org
Recently, there has been an increased interest in imaging different pulmonary disorders
using PET techniques. Previous work has shown, for static PET/CT, that air content in the …

Correlation of 68Ga ventilation–perfusion PET/CT with pulmonary function test indices for assessing lung function

PY Le Roux, S Siva, DP Steinfort… - Journal of Nuclear …, 2015 - Soc Nuclear Med
Pulmonary function tests (PFTs) are routinely used to assess lung function, but they do not
provide information about regional pulmonary dysfunction. We aimed to assess correlation …