The lipid metabolic landscape of cancers and new therapeutic perspectives

W Wang, L Bai, W Li, J Cui - Frontiers in oncology, 2020 - frontiersin.org
Lipid metabolism reprograming, as a hallmark of malignancy, has received renewed interest
in recent years in such areas as energy sources, cell membrane components, and signaling …

Lipid metabolism in cancer progression and therapeutic strategies

Y Fu, T Zou, X Shen, PJ Nelson, J Li, C Wu, J Yang… - MedComm, 2021 - Wiley Online Library
Dysregulated lipid metabolism represents an important metabolic alteration in cancer. Fatty
acids, cholesterol, and phospholipid are the three most prevalent lipids that act as energy …

[HTML][HTML] Lipid metabolism and cancer

X Bian, R Liu, Y Meng, D Xing, D Xu, Z Lu - Journal of Experimental …, 2021 - rupress.org
Dysregulation in lipid metabolism is among the most prominent metabolic alterations in
cancer. Cancer cells harness lipid metabolism to obtain energy, components for biological …

Greasing the wheels of the cancer machine: the role of lipid metabolism in cancer

MT Snaebjornsson, S Janaki-Raman, A Schulze - Cell metabolism, 2020 - cell.com
Altered lipid metabolism is among the most prominent metabolic alterations in cancer.
Enhanced synthesis or uptake of lipids contributes to rapid cancer cell growth and tumor …

Lipids in the tumor microenvironment: From cancer progression to treatment

KC Corn, MKA Windham, M Rafat - Progress in lipid research, 2020 - Elsevier
Over the past decade, the study of metabolic abnormalities in cancer cells has risen
dramatically. Cancer cells can thrive in challenging environments, be it the hypoxic and …

Lipid metabolism in oncology: why it matters, how to research, and how to treat

Y Matsushita, H Nakagawa, K Koike - Cancers, 2021 - mdpi.com
Simple Summary Metabolic reprogramming is gaining attentions as a hallmark of cancers.
However, lipid metabolism has been difficult to analyze due to technical problems. In recent …

Lipid metabolism and cancer

H Cheng, M Wang, J Su, Y Li, J Long, J Chu, X Wan… - Life, 2022 - mdpi.com
Lipid metabolism is involved in the regulation of numerous cellular processes, such as cell
growth, proliferation, differentiation, survival, apoptosis, inflammation, movement, membrane …

Aberrant lipid metabolism in cancer cells–the role of oncolipid‐activated signaling

U Ray, SS Roy - The FEBS journal, 2018 - Wiley Online Library
Metabolic activity of malignant cells is very different from that of their nontransformed
equivalents, which establishes metabolic reprogramming as an important hallmark of every …

[HTML][HTML] New dawn for cancer cell death: emerging role of lipid metabolism

C Zhang, N Zhu, H Li, Y Gong, J Gu, Y Shi, D Liao… - Molecular …, 2022 - Elsevier
Background Resistance to cell death, a protective mechanism for removing damaged cells,
is a “Hallmark of Cancer” that is essential for cancer progression. Increasing attention to …

Emerging roles of lipid metabolism in cancer progression

C Corbet, O Feron - Current Opinion in Clinical Nutrition & …, 2017 - journals.lww.com
To proliferate, metastasize, or resist stress conditions imposed by the microenvironment,
many cancer cells rely on fatty acid β-oxidation to generate acetyl-CoA and fuel the TCA …