Tumor-secreted extracellular vesicles (EVs) including microvesicles (MVs) and exosomes,
classified according to their sub-cellular origin [1], are critical mediators of intercellular …

Chronic lymphocytic leukemia (CLL) is a B-lymphoproliferative disease, which consists of
the abnormal proliferation of CD19/CD5/CD20/CD23 positive lymphocytes in blood and …

Extracellular vesicles have been described in non-paracrine cellular interactions in cancer.
We report a similar phenomenon in B-cell precursor (BCP) acute lymphoblastic leukaemia …

Human tumors constitutively release endosome-derived microvesicles, transporting a broad
array of biologically active molecules with potential modulatory effects on different immune …

For a long time, myeloid-derived suppressor cells (MDSCs) dilated in circulation system of
colorectal cancer (CRC) patients have been puzzling clinicians. Various evidence shows …

Extracellular vesicles (EVs) facilitate the extracellular transfer of proteins, lipids, and nucleic
acids and mediate intercellular communication among multiple cells in the tumour …

The tumor microenvironment consists of cancer cells and various stromal cells, including
macrophages, which exhibit diverse phenotypes with either pro-inflammatory (M1) or anti …

In chronic lymphocytic leukemia (CLL), monocytes and macrophages are skewed toward
protumorigenic phenotypes, including the release of tumor-supportive cytokines and the …

Small extracellular vesicles (sEVs) are nanoparticles responsible for cell-to-cell
communication released by healthy and cancer cells. Different roles have been described …

Extracellular vesicles (EVs) are important cell-to-cell communication mediators. This paper
focuses on the regulatory role of tumor-derived EVs on macrophages. It aims to investigate …