Mitochondria are essential for ensuring numerous fundamental physiological processes
such as cellular energy, redox balance, modulation of Ca2+ signaling and important …

Mitochondrial Ca2+ accumulation is a tightly controlled process, in turn regulating functions
as diverse as aerobic metabolism and induction of cell death. The link between Ca2+ (dys) …

Mitochondria are essential for proper cellular function through their critical roles in ATP
synthesis, reactive oxygen species production, calcium (Ca2+) buffering, and apoptotic …

Mitochondria play key roles in ATP supply, calcium homeostasis, redox balance control and
apoptosis, which in neurons are fundamental for neurotransmission and to allow synaptic …

Functional mitochondria are vital to accomplish their key role in the cell, by maintaining the
energy metabolism, buffering of the Ca 2+ signal and directing the cell death mechanism …

Understanding the mechanisms of neuronal dysfunction and death represents a major
frontier in contemporary medicine, involving the acute cell death in stroke, and the attrition of …

Abstract Mitochondrial calcium (Ca2+) dynamics play critical roles in regulating vital
physiological conditions in the brain. Importantly, Mitochondria‐associated endoplasmic …

Over recent years, a renewed interest in mitochondria in the field of Ca2+ signalling has
highlighted their central role in regulating important physiological and pathological events in …

The versatility of mitochondrial metabolism and its fine adjustments to specific physiological
or pathological conditions regulate fundamental cell pathways, ranging from proliferation to …

Calcium (Ca2+) is a versatile secondary messenger involved in the regulation of a plethora
of different signaling pathways for cell maintenance. Specifically, intracellular Ca2+ …