Diffusion tensor histology holds great promise for quantitative characterization of structural
connectivity in mouse models of neurological and psychiatric conditions. There has been …

Methods have been developed to allow quantitative connectivity of the whole fixed mouse
brain by means of magnetic resonance imaging (MRI). We have translated what we have …

Tractography combined with regions of interest (ROIs) has been used to non-invasively
study the structural connectivity of the cortex as well as to assess the reliability of these …

Interest in structural brain connectivity has grown with the understanding that abnormal
neural connections may play a role in neurologic and psychiatric diseases. Small animal …

The engineering of a 3 T human MRI scanner equipped with 300 mT/m gradients–the
strongest gradients ever built for an in vivo human MRI scanner–was a major component of …

Tremendous efforts have been made in the last decade to advance cutting-edge MRI
technology in pursuit of mapping structural connectivity in the living human brain with …

Diffusion magnetic resonance imaging has been widely used in both clinical and preclinical
studies to characterize tissue microstructure and structural connectivity. The diffusion MRI …

Background∎ Functional networks It is increasingly recognized that to fully understand the
function of the brain the 'localizationist'approach of yesteryear is no longer valid; rather, the …

Network approaches provide sensitive biomarkers for neurological conditions, such as
Alzheimer's disease (AD). Mouse models can help advance our understanding of underlying …

The global structural connectivity of the brain, the human connectome, is now accessible at
millimeter scale with the use of MRI. In this paper, we describe an approach to map the …