In 2002, I attended the Ninth Session of the International Bioethics Committee of UNESCO in
Montreal, and I still vividly remember when the audience discussed the report on …

Since the first clinical preimplantation genetic diagnosis (PGD) cycles carried out in 1989,
continuous technical improvements have supported progression from what was initially …

ABSTRACT STUDY QUESTION What are the trends and developments in preimplantation
genetic testing (PGT) in 2018 as compared to previous years? SUMMARY ANSWER The …

Background The first genetic testing on preimplantation embryos (PGT-M) was performed for
single gene disorders. Due to the costs and health risks associated with IVF, PGT-M was …

Polygenic embryo screening (PES)—the use of polygenic risk scores for complex
phenotypes as a component of preimplantation genetic testing (PGT)—has emerged as a …

This chapter on the ethics of human reproductive genetics focuses on current debates in
three corners of the field of medically assisted reproduction (MAR). First, we discuss …

The introduction of comprehensive testing techniques, such as microarray technology or
whole genome sequencing, in embryo testing has the potential to change the practice of …

STUDY QUESTION Is there an efficient and cost-effective detection platform for different
genetic conditions about embryos? SUMMARY ANSWER A multifunctional haplotyping …

Preimplantation genetic testing (PGT) comprises a wide range of molecular techniques that
are utilized during assisted reproduction and in vitro fertilization treatment for a range of …

In this review, we evaluate the different modalities of embryo genetic testing including
preimplantation genetic testing for aneuploidy (PGT-A), for monogenic/single-gene …