Reassessment of the proteomic composition and function of extracellular vesicles in the seminal plasma

H Wang, Y Zhu, C Tang, Z Zhou, Z Wang, Z Li… - …, 2022 - academic.oup.com
Seminal plasma contains a high concentration of extracellular vesicles (EVs). The
heterogeneity of small EVs or the presence of nonvesicular extracellular matter (NV) pose …

[HTML][HTML] Seminal extracellular vesicles and their involvement in male (in) fertility: A systematic review

A Parra, L Padilla, X Lucas… - International Journal of …, 2023 - mdpi.com
Seminal plasma contains numerous extracellular vesicles (sEVs). Since sEVs are
apparently involved in male (in) fertility, this systematic review focused on studies …

The effects of boar seminal plasma extracellular vesicles on sperm fertility

Z Xu, Y Xie, C Wu, T Gu, X Zhang, J Yang, H Yang… - Theriogenology, 2024 - Elsevier
Extracellular vesicles (EVs) are abundant in body fluid and are critical in cell interaction.
Seminal plasma contains numerous EVs which affecting sperm function via transferring …

Microfluidics facilitating the use of small extracellular vesicles in innovative approaches to male infertility

DM Goss, SA Vasilescu, G Sacks, DK Gardner… - Nature Reviews …, 2023 - nature.com
Sperm are transcriptionally and translationally quiescent and, therefore, rely on the seminal
plasma microenvironment for function, survival and fertilization of the oocyte in the oviduct …

[HTML][HTML] Immunophenotype profile by flow cytometry reveals different subtypes of extracellular vesicles in porcine seminal plasma

I Barranco, A Alvarez-Barrientos, A Parra… - Cell Communication and …, 2024 - Springer
Background Porcine seminal plasma (SP) is endowed with a heterogeneous population of
extracellular vesicles (sEVs). This study evaluated the immunophenotypic profile by high …

Quantitative proteomic analysis of seminal plasma, sperm membrane proteins, and seminal extracellular vesicles suggests vesicular mechanisms aid in the removal …

T Leahy, JP Rickard, T Pini, BM Gadella… - …, 2020 - Wiley Online Library
Quantitative proteomic studies are contributing greatly to the understanding of the
spermatozoon through the provision of detailed information on the proteins spermatozoa …

The emerging role of extracellular vesicles in the testis

Y Ma, QW Ma, Y Sun, XF Chen - Human Reproduction, 2023 - academic.oup.com
Extracellular vesicles (EVs) are nano-sized membrane-bounded particles, released by all
cells and capable of transporting bioactive cargoes, proteins, lipids, and nucleic acids, to …

Progress in understanding the functional roles of extracellular vesicles in reproduction

TT Han, LI Wei, GP Li - Biomedical and Environmental Sciences, 2020 - Elsevier
Exosomes, a type of extracellular vesicles (EVs), were first discovered in sheep reticulocytes
in 1983 [1], and after four years, the name 'exosome'was officially given to them. A variety of …

[HTML][HTML] The transformative impact of extracellular vesicles on developing sperm

MP Rimmer, CD Gregory… - Reproduction and …, 2021 - raf.bioscientifica.com
Objective To review the role of extracellular vesicles (EVs) released from the male
reproductive tract and their impact on developing sperm. We discuss how sperm exiting the …

[HTML][HTML] Exosome composition and seminal plasma proteome: A promising source of biomarkers of male infertility

L Candenas, R Chianese - International journal of molecular sciences, 2020 - mdpi.com
Infertility has become a global health issue, with approximately 50% of infertility cases
generated by disorders in male reproduction. Spermatozoa are conveyed towards female …