Organs transplanted from deceased donors provide effective life-saving and lifeenhancing
treatment for many individuals with end-stage organ failure. Most of the donors have been …

Abstract Experiments in Cape Town in the 1980s demonstrated that acute brain death is
followed by massive catecholamine release resulting in systemic hypertension, acute left …

Organ transplantation often depends on obtaining functioning organs from a donor who has
recently died. This review presents a structured approach to management of the care of the …

Significant systemic changes occur following neurologic insult and subsequent brain death.
If left untreated, the hemodynamic instability and neuroendocrine alterations that ensue may …

Background. Brain death results in adverse pathophysiologic effects in many cadaveric
donors, resulting in cardiovascular instability and poor organ perfusion. Hormonal …

BACKGROUND Organ shortage is an ongoing problem in the United States. Most donor
organs are procured following brain death and a significant portion of brain-dead donors …

Hormonal replacement therapy to brain‐dead potential organ donors remains controversial.
A retrospective study was carried out of hormonal therapy on procurement of organs in 63 …

Background. Brain death results in cardiovascular instability and poor organ perfusion in
many brain-dead donors. Hormonal resuscitation stabilizes certain brain-dead donors and is …

There are still many controversial aspects regarding which method is best for managing
organ donors to prevent, lessen, or even reverse the organ alterations associated with brain …

Patients determined to be neurologically deceased exhibit potentially harmful changes in
various endocrine pathways due to disruptions of the body's neurohormonal control …