Background Hemagglutinin (HA) and neuraminidase (NA) are the two major surface
glycoproteins of influenza viruses and the main targets of vaccine-induced antibodies (Abs) …

The spread of the recently emerged, highly pathogenic H5N1 avian influenza virus has
raised concern. Preclinical studies suggest that passive immunotherapy could be a new …

Influenza virus infections pose a continuous threat to human health. Although vaccines
function as a preventive and protective tool, they may not be effective due to antigen drift or …

Abstract Avian A (H5N1) influenza virus poses an elevated zoonotic threat to humans, and
no pharmacological products are currently registered for fast-acting pre-exposure protection …

Influenza A viruses are a diverse species that include 16 true hemagglutinin (HA) subtypes
and 9 true neuraminidase (NA) subtypes. While the antigenicity of many HA subtypes is …

Influenza A virus (IAV), a major cause of human morbidity and mortality, continuously
evolves in response to selective pressures. Stem-directed, broadly neutralizing antibodies …

Understanding the mechanism of protective antibody recognition against highly pathogenic
avian influenza A virus H5N1 in humans is critical for the development of effective therapies …

ABSTRACT A human monoclonal heterosubtypic antibody, MAb 3.1, with its heavy chain
encoded by VH3-30, was isolated using phage display with immobilized hemagglutinin (HA) …

ABSTRACT Between November 2013 and February 2014, China reported three human
cases of H10N8 influenza virus infection in the Jiangxi province, two of which were fatal …

Influenza A viruses are classified into 16 subtypes according to the serotypes of
hemagglutinin (HA). It is generally thought that neutralizing antibodies (Abs) are not broadly …