Malaria is a global health problem leading to the death of 435,000 cases in tropical and sub-
tropical zones. Spread and emergence of increasing resistance to the antimalarial drugs are …

Background Chemotherapy is crucial in the fight against malaria. The rise of resistance to
most antimalarial medicines has been a serious hurdle to effective treatment. Artemisinin …

Artemisinin-based combination (ACT) therapy is the mainstay for malaria treatment.
However, Plasmodium parasite with decreased susceptibility to ACT has emerged. Hence, it …

Introduction: The huge cost of de-novo drug development and the problem of multidrug
resistance by plasmodium parasites has made research on drugs with potential for …

Background: Malaria is common in regions like sub-Saharan Africa and South East Asia,
where it results in millions of mortalities per year. Resistance to currently available …

Objective: The concurrent use of antibiotics and antimalarial drugs may increase
Plasmodium susceptibility. Clindamycin (C) is an antibiotic with potential antiplasmodial …

Objective: The aim was to determine the antimalarial drug effectiveness of the combination
therapy model of 80% ethanolic extract of sambiloto (EES) and chloroquine on Plasmodium …

Antiplasmodial activity of the 80% methanolic extract of Artemisia abyssinica (A. abyssinica)
aerial part against chloroquine sensitive Plasmodium berghei (P. berghei) in mice using the …

This study examined the antiplasmodial effect of desloratadine-dihydroartemisinin-
piperaquine (DL/D/P) on Plasmodium berghei infected mice. Adult mice (22–25 g) were …

Background Artemisinin-based combination therapy (ACT) has been adopted as national
policy for the first-line treatment in large number of malaria-endemic regions. However …