Inflammation and immune responses in atherosclerosis

DR Greaves, KM Channon - Trends in immunology, 2002 - cell.com
Recent studies have highlighted the role of inflammatory mediators and the cells of the
innate and adaptive immune response in the initiation, growth and rupture of atherosclerotic …

T cells in atherosclerosis

K Tse, H Tse, J Sidney, A Sette… - International immunology, 2013 - academic.oup.com
Atherosclerosis is a chronic inflammatory disease of the artery wall. Atherosclerotic lesions
contain monocytes, macrophages, smooth muscle cells and T lymphocytes. Here, we review …

Antigen-presenting dendritic cells in atherosclerosis

J Gil-Pulido, A Zernecke - European journal of pharmacology, 2017 - Elsevier
Atherosclerosis is characterized by lipid accumulation and chronic inflammation of the
arterial wall, involving both innate and adaptive immune responses. Accumulation of lipid …

Natural regulatory T cells control the development of atherosclerosis in mice

H Ait-Oufella, BL Salomon, S Potteaux… - Nature medicine, 2006 - nature.com
Atherosclerosis is an immunoinflammatory disease elicited by accumulation of lipids in the
artery wall and leads to myocardial infarction and stroke,. Here, we show that naturally …

The influence of the regulatory T lymphocytes on atherosclerosis

I Gotsman, R Gupta, AH Lichtman - … , thrombosis, and vascular …, 2007 - Am Heart Assoc
Atherosclerosis is complex inflammatory disease of the arterial wall, in which T lymphocytes
play a significant role. 1 Since the recognition that T lymphocytes are present in human …

Innate and adaptive immunity in atherosclerosis

RRS Packard, AH Lichtman, P Libby - Seminars in immunopathology, 2009 - Springer
Atherosclerosis, a chronic inflammatory disorder, involves both the innate and adaptive arms
of the immune response that mediate the initiation, progression, and ultimate thrombotic …

Atherosclerosis—an immune disease: the Anitschkov Lecture 2007

GK Hansson - Atherosclerosis, 2009 - Elsevier
Atherosclerosis is an inflammatory disease. This article reviews the emergence of this
concept from studies of patients and their lesions, experimental animal models, and …

T cell subsets and functions in atherosclerosis

R Saigusa, H Winkels, K Ley - Nature Reviews Cardiology, 2020 - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall and the primary
underlying cause of cardiovascular disease. Data from in vivo imaging, cell-lineage tracing …

Cell-mediated immunity in atherosclerosis

GK Hansson - Current opinion in lipidology, 1997 - journals.lww.com
Immunocompetent cells infiltrate atherosclerotic plaques of all stages. Plaque-infiltrating T-
cells recognize oxidized LDL and heat shock proteins and this elicits antibody responses …

The emerging role of Th1 cells in atherosclerosis and its implications for therapy

J Chen, X Xiang, L Nie, X Guo, F Zhang… - Frontiers in …, 2023 - frontiersin.org
Atherosclerosis is a chronic progressive inflammatory disease of the large and medium-
sized artery walls. The molecular mechanisms regulating the onset and progression of …