An investigation has been made into the exchange of thyroxine between human plasma and
the perfused rat liver. A stop-flow method was used to hold plasma within the liver sinusoids …

Radioactively labeled thyroxine was administered to rats, and after 1 to 20 hr their livers
were isolated and perfused with pooled rat blood. It was found that, during the perfusion …

1. An examination has been made of the uptake of [131I] L‐thyroxine and L‐3, 5, 3′‐tri‐
iodothyronine by the perfused rat liver. 2. With no serum in the perfusion fluid and at flow …

To investigate the mechanism by which thyroxine (T4) in plasma enters hepatic cells, we
measured the rate constants for uptake of free T4 by the perfused rat liver and for …

1. An examination has been made of the uptake of thyroxine by rat livers perfused with very
dilute solutions of thyroxine‐binding globulin (TBG) and thyroxine‐binding pre‐albumin …

The transport of [125I] thyroxine (T4) and [125I] triiodothyronine (T3) into liver was
investigated with a tissue sampling-portal vein injection technique in the anesthetized rat …

Tissue uptake of intravenously administered 125I-thyroxine (125I-T4) was estimated in liver
and kidney after appropriate corrections for tracer T4 associated with plasma proteins in …

Rates of hepatic uptake of thyroxine (T4) from dilute solutions of five different plasma T4-
binding proteins were measured in the isolated perfused rat liver using an indicator dilution …

Administration of phenobarbital to rats in a dosage schedule previously demonstrated to
increase hepatocellular binding of thyroxine results in increased hormonal turnover, due …

The disapperarance of loading doses of thyroxine (T4)(100–20 000 μg T4 iv per rat
weighing about 400 g) was measured with the aid of new technique allowing frequent blood …