Astrogliopathology in neurological, neurodevelopmental and psychiatric disorders
A Verkhratsky, V Parpura - Neurobiology of disease, 2016 - Elsevier
Astroglial cells represent a main element in the maintenance of homeostasis and providing
defense to the brain. Consequently, their dysfunction underlies many, if not all, neurological …
defense to the brain. Consequently, their dysfunction underlies many, if not all, neurological …
Astrogliopathology: a central element of neuropsychiatric diseases?
A Verkhratsky, JJ Rodríguez, L Steardo - The Neuroscientist, 2014 - journals.sagepub.com
Astroglia are the homoeostatic cells of the central nervous system that control a normal
function of synaptically connected neuronal networks and contribute to brain defense …
function of synaptically connected neuronal networks and contribute to brain defense …
Astrocytes: a central element in neurological diseases
The neurone-centred view of the past disregarded or downplayed the role of astroglia as a
primary component in the pathogenesis of neurological diseases. As this concept is …
primary component in the pathogenesis of neurological diseases. As this concept is …
Why are astrocytes important?
A Verkhratsky, M Nedergaard, L Hertz - Neurochemical research, 2015 - Springer
Astrocytes, which populate the grey and white mater of the brain and the spinal cord are
highly heterogeneous in their morphology and function. These cells are primarily …
highly heterogeneous in their morphology and function. These cells are primarily …
Pathobiology of neurodegeneration: the role for astroglia
A Verkhratsky, R Zorec, JJ Rodriguez… - Opera medica et …, 2016 - cyberleninka.ru
The common denominator of neurodegenerative diseases, which mainly affect humans, is
the progressive death of neural cells resulting in neurological and cognitive deficits …
the progressive death of neural cells resulting in neurological and cognitive deficits …
Astrogliosis: an integral player in the pathogenesis of Alzheimer's disease
LM Osborn, W Kamphuis, WJ Wadman, EM Hol - Progress in neurobiology, 2016 - Elsevier
Alzheimer's disease is the main cause of dementia in the elderly and begins with a subtle
decline in episodic memory followed by a more general decline in overall cognitive abilities …
decline in episodic memory followed by a more general decline in overall cognitive abilities …
Astroglia in neurological diseases
A Verkhratsky, JJ Rodríguez, V Parpura - Future neurology, 2013 - Taylor & Francis
Astroglia encompass a subset of versatile glial cells that fulfill a major homeostatic role in the
mammalian brain. Since any brain disease results from failure in brain homeostasis …
mammalian brain. Since any brain disease results from failure in brain homeostasis …
Astrocytes in human central nervous system diseases: a frontier for new therapies
A Verkhratsky, A Butt, B Li, P Illes, R Zorec… - … and Targeted Therapy, 2023 - nature.com
Astroglia are a broad class of neural parenchymal cells primarily dedicated to homoeostasis
and defence of the central nervous system (CNS). Astroglia contribute to the …
and defence of the central nervous system (CNS). Astroglia contribute to the …
General pathophysiology of astroglia
Astroglial cells are involved in most if not in all pathologies of the brain. These cells can
change the morpho-functional properties in response to pathology or innate changes of …
change the morpho-functional properties in response to pathology or innate changes of …
Astroglial correlates of neuropsychiatric disease: From astrocytopathy to astrogliosis
Complex roles for astrocytes in health and disease continue to emerge, highlighting this
class of cells as integral to function and dysfunction of the nervous system. In particular …
class of cells as integral to function and dysfunction of the nervous system. In particular …