Objective: To determine whether chemokines, which play a pivotal role in monocyte/
macrophage trafficking, modulate macrophage infiltration into and activation in the adipose …

Adipose tissue expression and circulating concentrations of monocyte chemoattractant
protein-1 (MCP-1) correlate positively with adiposity. To ascertain the roles of MCP-1 …

OBJECTIVE—We sought to evaluate the entire picture of all monocyte chemotactic factors
that potentially contribute to adipose tissue macrophage accumulation in obesity …

Adipocytes secrete a variety of bioactive molecules that affect the insulin sensitivity of other
tissues. We now show that the abundance of monocyte chemoattractant protein–1 (MCP-1) …

Adipocytes not only store energy, but also secrete biologically active molecules called
adipocytokines, which play a pivotal role in adipocyte‐related pathological processes such …

BACKGROUND: Monocyte chemoattractant protein-1 (MCP-1) is a chemokine involved in
monocyte recruitment during inflammation whose plasma level is elevated in obesity …

The MCP-1 (monocyte chemoattractant protein-1)/CCR2 (CC motif chemokine receptor-2)
pathway may play a role in macrophage infiltration into obese adipose tissue. Here we …

Objective: To examine the effect of a high‐fat diet on gene expression in adipose tissues
and to determine induction kinetics of adipose monocyte chemoattractant protein‐1 and− 3 …

Macrophage-mediated inflammation is a key component of insulin resistance; however, the
initial events of monocyte migration to become tissue macrophages remain poorly …

Context: Low-grade inflammation in adipose tissue may contribute to insulin resistance in
obesity. However, the roles of individual inflammatory mediators in adipose tissue are poorly …