Involvement of pmrAB and phoPQ in Polymyxin B Adaptation and Inducible Resistance in Non-Cystic Fibrosis Clinical Isolates of Pseudomonas aeruginosa
KN Schurek, JLM Sampaio, CRV Kiffer… - Antimicrobial agents …, 2009 - Am Soc Microbiol
During investigation of susceptibility testing methods for polymyxins, 24 multidrug-resistant
clinical isolates of Pseudomonas aeruginosa were observed to have a distinct, reproducible …
clinical isolates of Pseudomonas aeruginosa were observed to have a distinct, reproducible …
Adaptive resistance to cationic compounds in Pseudomonas aeruginosa
A Skiada, A Markogiannakis, D Plachouras… - International journal of …, 2011 - Elsevier
Adaptive resistance is an autoregulated phenomenon characterised by induction of
resistance in the presence of drug and reversal to the sensitive phenotype in its absence …
resistance in the presence of drug and reversal to the sensitive phenotype in its absence …
PmrB mutations promote polymyxin resistance of Pseudomonas aeruginosa isolated from colistin-treated cystic fibrosis patients
SM Moskowitz, MK Brannon, N Dasgupta… - Antimicrobial agents …, 2012 - Am Soc Microbiol
Pseudomonas aeruginosa can develop resistance to polymyxin and other cationic
antimicrobial peptides. Previous work has shown that mutations in the PmrAB and PhoPQ …
antimicrobial peptides. Previous work has shown that mutations in the PmrAB and PhoPQ …
Regulation of polymyxin resistance and adaptation to low-Mg2+ environments
EA Groisman, J Kayser, FC Soncini - Journal of bacteriology, 1997 - Am Soc Microbiol
The PmrA-PmrB two-component system of Salmonella typhimurium controls resistance to
the peptide antibiotic polymyxin B and to several antimicrobial proteins from human …
the peptide antibiotic polymyxin B and to several antimicrobial proteins from human …
A Two-Component Regulatory System Interconnects Resistance to Polymyxins, Aminoglycosides, Fluoroquinolones, and β-Lactams in Pseudomonas aeruginosa
C Muller, P Plésiat, K Jeannot - Antimicrobial agents and …, 2011 - Am Soc Microbiol
Constitutive overexpression of the active efflux system MexXY/OprM is a major cause of
resistance to aminoglycosides, fluoroquinolones, and cefepime in clinical strains of …
resistance to aminoglycosides, fluoroquinolones, and cefepime in clinical strains of …
The two-component system CprRS senses cationic peptides and triggers adaptive resistance in Pseudomonas aeruginosa independently of ParRS
L Fernández, H Jenssen, M Bains… - Antimicrobial agents …, 2012 - Am Soc Microbiol
Cationic antimicrobial peptides pass across the outer membrane by interacting with
negatively charged lipopolysaccharide (LPS), leading to outer membrane permeabilization …
negatively charged lipopolysaccharide (LPS), leading to outer membrane permeabilization …
Analysis of the networks controlling the antimicrobial-peptide-dependent induction of Klebsiella pneumoniae virulence factors
E Llobet, MA Campos, P Giménez… - Infection and …, 2011 - Am Soc Microbiol
Antimicrobial peptides (APs) impose a threat to the survival of pathogens, and it is
reasonable to postulate that bacteria have developed strategies to counteract them …
reasonable to postulate that bacteria have developed strategies to counteract them …
PhoQ mutations promote lipid A modification and polymyxin resistance of Pseudomonas aeruginosa found in colistin-treated cystic fibrosis patients
AK Miller, MK Brannon, L Stevens… - Antimicrobial agents …, 2011 - Am Soc Microbiol
Pseudomonas aeruginosa can develop resistance to polymyxin and other cationic
antimicrobial peptides. Previous work has shown that mutations in the PmrAB and PhoPQ …
antimicrobial peptides. Previous work has shown that mutations in the PmrAB and PhoPQ …
Characterization of the polymyxin B resistome of Pseudomonas aeruginosa
L Fernández, C Álvarez-Ortega, I Wiegand… - Antimicrobial agents …, 2013 - Am Soc Microbiol
Multidrug resistance in Pseudomonas aeruginosa is increasingly becoming a threat for
human health. Indeed, some strains are resistant to almost all currently available antibiotics …
human health. Indeed, some strains are resistant to almost all currently available antibiotics …
[HTML][HTML] Interactions of lipopolysaccharide and polymyxin studied by NMR spectroscopy
J Mares, S Kumaran, M Gobbo, O Zerbe - Journal of Biological Chemistry, 2009 - ASBMB
In the light of occurrence of bacterial strains with multiple resistances against most
antibiotics, antimicrobial peptides that interact with the outer layer of Gram-negative bacteria …
antibiotics, antimicrobial peptides that interact with the outer layer of Gram-negative bacteria …