An observational cohort study of bevacizumab and chemotherapy in metastatic colorectal cancer patients: safety and efficacy with analysis by age group

E Tahover, A Hubert, M Temper, A Salah, T Peretz… - Targeted …, 2015 - Springer
Bevacizumab improves survival when added to chemotherapy in metastatic colorectal
cancer (mCRC). We assessed the safety and efficacy of bevacizumab in mCRC patients≥ …

Efficacy and toxicity of bevacizumab on combination with chemotherapy in different lines of treatment for metastatic colorectal carcinoma

I Kiss, Z Bortlicek, B Melichar, A Poprach… - Anticancer …, 2014 - ar.iiarjournals.org
The aim of the present study was to describe treatment outcomes for bevacizumab in
combination with chemotherapy based on data from the Czech registry of targeted therapies …

Survival for metastatic colorectal cancer in the bevacizumab era: a population-based analysis

DJ Renouf, HJ Lim, C Speers, D Villa, S Gill… - Clinical colorectal …, 2011 - Elsevier
Background As of 2006, bevacizumab was available for the treatment of metastatic
colorectal cancer (mCRC) in British Columbia (BC). This study compares survival between …

Clinical outcomes associated with bevacizumab-containing treatment of metastatic colorectal cancer: the BRiTE observational cohort study

M Kozloff, MU Yood, J Berlin, PJ Flynn… - The …, 2009 - academic.oup.com
Abstract Background. The Bevacizumab Regimens' Investigation of Treatment Effects
(BRiTE) study is a prospective, observational cohort study designed to elucidate safety and …

Bevacizumab plus chemotherapy as first-line treatment for patients with metastatic colorectal cancer: results from a large German community-based observational …

A Stein, V Petersen, M Schulze, J Seraphin… - Acta …, 2015 - Taylor & Francis
Background. After approval of bevacizumab in Germany in 2005 for the treatment of
unresectable advanced or refractory colorectal cancer (CRC), this observational cohort …

Safety of bevacizumab in treating metastatic colorectal cancer: a systematic review and meta-analysis of all randomized clinical trials

F Dai, L Shu, Y Bian, Z Wang, Z Yang, W Chu… - Clinical drug …, 2013 - Springer
Background and objective The incidence rates of colorectal cancer (CRC) are increasing in
a number of different regions, and recent studies have indicated that addition of …

Efficacy and safety of bevacizumab in metastatic colorectal cancer: pooled analysis from seven randomized controlled trials

HI Hurwitz, NC Tebbutt, F Kabbinavar… - The …, 2013 - academic.oup.com
Purpose. This analysis pooled individual patient data from randomized controlled trials
(RCTs) to more thoroughly examine clinical outcomes when adding bevacizumab to …

A meta-analysis of randomized controlled trials comparing chemotherapy plus bevacizumab with chemotherapy alone in metastatic colorectal cancer

Y Cao, A Tan, F Gao, L Liu, C Liao, Z Mo - International journal of …, 2009 - Springer
Purpose Bevacizumab has demonstrated survival benefit in metastatic colorectal cancer
(mCRC) patients when combined with chemotherapy. Several randomized clinical studies …

Chemotherapy with bevacizumab for metastatic colorectal cancer: a retrospective review of 181 Japanese patients

S Saito, N Hayashi, N Sato, M Iwatsuki, Y Baba… - International journal of …, 2013 - Springer
Background There has so far been little information on the clinical effect of bevacizumab
against colorectal cancer in Japan. Hence, this study was conducted to retrospectively …

Bevacizumab treatment for metastatic colorectal cancer in real-world clinical practice

IM Dinu, M Mihăilă, MM Diculescu, VM Croitoru… - Medicina, 2023 - mdpi.com
Background and Objectives: Colorectal cancer (CRC) is a leading cause of cancer-related
mortality and morbidity worldwide. Bevacizumab was approved for the treatment of …