Functional connectomics of affective and psychotic pathology
Converging evidence indicates that groups of patients with nominally distinct psychiatric
diagnoses are not separated by sharp or discontinuous neurobiological boundaries. In …
diagnoses are not separated by sharp or discontinuous neurobiological boundaries. In …
Brain structure in people at ultra-high risk of psychosis, patients with first-episode schizophrenia, and healthy controls: a VBM study
I Nenadic, M Dietzek, N Schönfeld, C Lorenz… - Schizophrenia …, 2015 - Elsevier
Early intervention research in schizophrenia has suggested that brain structural alterations
might be present in subjects at high risk of developing psychosis. The heterogeneity of …
might be present in subjects at high risk of developing psychosis. The heterogeneity of …
Functional connectome organization predicts conversion to psychosis in clinical high-risk youth from the SHARP program
The emergence of prodromal symptoms of schizophrenia and their evolution into overt
psychosis may stem from an aberrant functional reorganization of the brain during …
psychosis may stem from an aberrant functional reorganization of the brain during …
Alterations in hippocampal connectivity across the psychosis dimension
Recent evidence demonstrates that hippocampal hyperactivity helps mediate psychosis.
Using resting state functional magnetic resonance imaging (rsfMRI), we examined …
Using resting state functional magnetic resonance imaging (rsfMRI), we examined …
Prefrontal inefficiency is associated with polygenic risk for schizophrenia
Considering the diverse clinical presentation and likely polygenic etiology of schizophrenia,
this investigation examined the effect of polygenic risk on a well-established intermediate …
this investigation examined the effect of polygenic risk on a well-established intermediate …
Brain anatomical abnormalities in high-risk individuals, first-episode, and chronic schizophrenia: an activation likelihood estimation meta-analysis of illness …
RCK Chan, X Di, GM McAlonan… - Schizophrenia bulletin, 2011 - academic.oup.com
Objective: The present study reviewed voxel-based morphometry (VBM) studies on high-risk
individuals with schizophrenia, patients experiencing their first-episode schizophrenia …
individuals with schizophrenia, patients experiencing their first-episode schizophrenia …
Brain heterogeneity in schizophrenia and its association with polygenic risk
Importance Between-individual variability in brain structure is determined by gene-
environment interactions, possibly reflecting differential sensitivity to environmental and …
environment interactions, possibly reflecting differential sensitivity to environmental and …