It is well known that the ω–3 fatty acids (ω–3-FAs; also known as n–3 fatty acids) can exert
potent anti-inflammatory effects,,,. Commonly consumed as fish products, dietary …

Free fatty acids provide an important energy source as nutrients, and act as signalling
molecules in various cellular processes,,,. Several G-protein-coupled receptors have been …

Diabetes, a disease in which carbohydrate and lipid metabolism are regulated improperly by
insulin, is a serious worldwide health issue,. Insulin is secreted from pancreatic β cells in …

The past decade has seen great progress in the understanding of the molecular
pharmacology, physiological function and therapeutic potential of G-protein-coupled …

Type 2 diabetes is a major health problem worldwide, and one of its key features is the
inability of elevated glucose to stimulate the release of sufficient amounts of insulin from …

Over the last decade, a subfamily of G protein-coupled receptors that are agonized by
endogenous and dietary free-fatty acids (FFA) has been discovered. These free-fatty acid …

Summary Omega-3 fatty acids (ω-3 FAs), DHA and EPA, exert anti-inflammatory effects, but
the mechanisms are poorly understood. Here, we show that the G protein-coupled receptor …

Diabetes, a disease in which the body does not produce or use insulin properly, is a serious
global health problem,,. Gut polypeptides secreted in response to food intake, such as …

G protein-coupled receptor 120 (GPR120) and PPARγ agonists each have insulin
sensitizing effects. But whether these two pathways functionally interact and can be …

The GPR119 receptor is expressed predominantly in pancreatic β cells and in
enteroendocrine cells. It is a major target for the development of anti-diabetic drugs that …