A microfluidic diode for sorting and immobilization of Caenorhabditis elegans

L Yang, T Hong, Y Zhang, JGS Arriola, BL Nelms… - Biomedical …, 2017 - Springer
Caenorhabditis elegans (C. elegans) is a powerful model organism extensively used in
studies of human aging and diseases. Despite the numerous advantages of C. elegans as a …

An Automated Microfluidic System for Morphological Measurement and Size-Based Sorting of C. Elegans

X Dong, P Song, X Liu - IEEE Transactions on Nanobioscience, 2019 - ieeexplore.ieee.org
This paper reports a vision-based automated microfluidic system for morphological
measurement and size-based sorting of the nematode worm C. elegans. Exceeding the …

Microfluidic-Assisted Caenorhabditis elegans Sorting: Current Status and Future Prospects

H Yuan, W Yuan, S Duan, K Jiao, Q Zhang… - Cyborg and Bionic …, 2023 - spj.science.org
Caenorhabditis elegans (C. elegans) has been a popular model organism for several
decades since its first discovery of the huge research potential for modeling human diseases …

Versatile size-dependent sorting of C. elegans nematodes and embryos using a tunable microfluidic filter structure

L Dong, M Cornaglia, T Lehnert, MAM Gijs - Lab on a Chip, 2016 - pubs.rsc.org
The roundworm Caenorhabditis elegans (C. elegans) is a powerful model organism for
addressing fundamental biological questions related to human disease and aging. Its life …

High-throughput age synchronisation of Caenorhabditis elegans

XC i Solvas, FM Geier, AM Leroi, JG Bundy… - Chemical …, 2011 - pubs.rsc.org
We present a passive microfluidic strategy for sorting adult C. elegans nematodes on the
basis of age and size. The separation mechanism takes advantage of phenotypic …

A microfluidic microfilter chip driven by electrotaxis and fluid flow for size-dependent C. elegans sorting with high purity and efficiency

X Wang, A Ge, L Hu, X Feng, W Du, BF Liu - Sensors and Actuators B …, 2018 - Elsevier
C. elegans is a leading model organism for addressing many fundamental biology issues.
Sufficient quantities of the worms with specific developmental stage are needed in C …

Fluorescence-based sorting of Caenorhabditis elegans via acoustofluidics

J Zhang, JH Hartman, C Chen, S Yang, Q Li, Z Tian… - Lab on a Chip, 2020 - pubs.rsc.org
Effectively isolating and categorizing large quantities of Caenorhabditis elegans (C.
elegans) based on different phenotypes is important for most worm research, especially …

Microfluidic Approaches for Manipulating, Imaging, and Screening C. elegans

BP Gupta, P Rezai - Micromachines, 2016 - mdpi.com
The nematode C. elegans (worm) is a small invertebrate animal widely used in studies
related to fundamental biological processes, disease modelling, and drug discovery. Due to …

A high-throughput device for size based separation of C. elegans developmental stages

X Ai, W Zhuo, Q Liang, PT McGrath, H Lu - Lab on a Chip, 2014 - pubs.rsc.org
Caenorhabditis elegans is a widely used model organism to study development, aging and
behavior. Many of these biological studies require staging a large number of worms to assay …

PDMS filter structures for size-dependent larval sorting and on-chip egg extraction of C. elegans

HB Atakan, F Ayhan, MAM Gijs - Lab on a Chip, 2020 - pubs.rsc.org
C. elegans-based assays require age-synchronized populations prior to experimentation to
achieve standardized sets of worm populations, due to which age-induced heterogeneous …