Nerve-binding fluorophores with near-infrared (NIR; 650 to 900 nm) emission could reduce
iatrogenic nerve injury rates by providing surgeons precise, real-time visualization of the …

Nerve damage is a major morbidity associated with numerous surgical interventions. Yet,
nerve visualization continues to challenge even the most experienced surgeons. A nerve …

Nerve preservation is an important issue during most surgery because accidental
transection or injury results in significant morbidity, including numbness, pain, weakness, or …

Fluorescence‐guided surgery (FGS) is poised to revolutionize surgical medicine through
near‐infrared (NIR) fluorophores for tissue‐and disease‐specific contrast. Clinical open and …

Iatrogenic nerve injury represents one of the most feared surgical complications and
remains a major morbidity across many surgical specialties. Currently, no clinically …

Objective: This review details the agents for fluorescence-guided nerve imaging in both
preclinical and clinical use to identify factors important in selecting nerve-specific fluorescent …

The ability to visualize and spare nerves during surgery is critical for avoiding chronic
morbidity, pain, and loss of function. Visualization of such critical anatomic structures is even …

Near‐infrared (NIR) fluorescence imaging can provide real‐time navigation for surgeons to
discriminate boundaries between lesions and healthy tissue, which serves as a promising …

A fundamental goal of many surgeries is nerve preservation, as inadvertent injury can lead
to patient morbidity including numbness, pain, localized paralysis and incontinence. Nerve …

Accidental transection or injury of nerves during surgeries leads to severe patient morbidity
and lowers the life quality of patients. The current imaging modality for nerves, such as …