Patients with chronic obstructive pulmonary disease (COPD) may develop hypoxemia and
pulmonary hypertension when exercising. To investigate whether inhaled nitric oxide (NO) …

Cigarette smoking is the most common factor responsible for the development of chronic
obstructive pulmonary disease (COPD) leading to oxidant overload in the lower airways …

Chronic obstructive pulmonary disease (COPD) is a progressive syndrome of expiratory
airflow limitation caused by chronic inflammation of the airways and lung parenchyma. The …

Airways inflammation has been associated with increased nitric oxide (NO) in the exhaled
breath. It was, therefore, questioned whether exhaled NO could act as an indicator of the …

In order to study neutrophil traffic In the lungs of humalls, weharvested autologous
neutrophils and redlolabeled them with Indlum-111 priorto reinjection. The~ ofthesa ['" …

Introduction Sputum eosinophilia occurs in approximately one-third of stable chronic
obstructive pulmonary disease (COPD) patients and can predict exacerbation risk and …

Some patients with severe asthma are difficult to control and suffer from frequent
exacerbations, whereas others remain stable with anti-inflammatory therapy. To investigate …

Study objectives To test the hypothesis that exhaled nitric oxide (NO) is increased in patients
with chronic bronchitis, and to compare the results with exhaled NO in patients with asthma …

In a former study in patients with severe chronic airflow obstruction (CAO),(forced expiratory
volume in one second (FEV1) ranging from 350-910 ml), we concluded that daily oral …

BACKGROUND Exhaled levels of nitric oxide (NO) are raised in asthma but the relationship
between exhaled NO levels and a direct measure of airway inflammation has not been …