Relationship between peripheral airway dysfunction, airway obstruction, and neutrophilic inflammation in COPD
RA O'donnell, C Peebles, JA Ward, A Daraker… - Thorax, 2004 - thorax.bmj.com
Background: Considerable research has been conducted into the nature of airway
inflammation in chronic obstructive pulmonary disease (COPD) but the relationship between …
inflammation in chronic obstructive pulmonary disease (COPD) but the relationship between …
Effects of fluticasone propionate in COPD patients with bronchial hyperresponsiveness
GT Verhoeven, J Hegmans, PGH Mulder, JM Bogaard… - Thorax, 2002 - thorax.bmj.com
Background: Treatment of chronic obstructive pulmonary disease (COPD) with inhaled
corticosteroids does not appear to be as effective as similar treatment of asthma. It seems …
corticosteroids does not appear to be as effective as similar treatment of asthma. It seems …
Impaired neutrophil chemotaxis in chronic obstructive pulmonary disease
T Yoshikawa, G Dent, J Ward, G Angco… - American journal of …, 2007 - atsjournals.org
Rationale: Neutrophilic airway inflammation is considered to be a major factor in the
pathogenesis of chronic obstructive pulmonary disease (COPD), with sputum and …
pathogenesis of chronic obstructive pulmonary disease (COPD), with sputum and …
Effects of inhaled and oral glucocorticoids on inflammatory indices in asthma and COPD.
VM Keatings, A Jatakanon, YM Worsdell… - American journal of …, 1997 - atsjournals.org
The role of glucocorticoids in the treatment of chronic obstructive pulmonary disease
(COPD) is controversial. We have previously described high numbers of neutrophils and …
(COPD) is controversial. We have previously described high numbers of neutrophils and …
[HTML][HTML] Association between cytokines in induced sputum and severity of chronic obstructive pulmonary disease
SS Hacievliyagil, H Gunen, LC Mutlu, AB Karabulut… - Respiratory …, 2006 - Elsevier
Cytokines are known to be increased in induced sputum in chronic obstructive pulmonary
disease (COPD). In this study, the relationship between the levels of interleukin-6 (IL-6) …
disease (COPD). In this study, the relationship between the levels of interleukin-6 (IL-6) …
Exhaled nitric oxide, systemic inflammation, and the spirometric response to inhaled fluticasone propionate in severe chronic obstructive pulmonary disease: a …
Background: A subset of patients with chronic obstructive pulmonary disease (COPD) may
respond more favorably to inhaled corticosteroids (ICS), but no simple method is currently …
respond more favorably to inhaled corticosteroids (ICS), but no simple method is currently …
Blood eosinophilia neither reflects tissue eosinophils nor worsens clinical outcomes in chronic obstructive pulmonary disease
G Turato, U Semenzato, E Bazzan… - American journal of …, 2018 - atsjournals.org
The role of the blood eosinophil count as a biomarker predictor of the frequency of
exacerbations and response to corticosteroid treatment in chronic obstructive pulmonary …
exacerbations and response to corticosteroid treatment in chronic obstructive pulmonary …
Expired nitric oxide after bronchoprovocation and repeated spirometry in patients with asthma
A Deykin, O Halpern, AF Massaro… - American journal of …, 1998 - atsjournals.org
Compared with normal individuals, subjects with asthma have elevated levels of expired
nitric oxide (NO). These levels are hypothesized to reflect the degree of airway inflammation …
nitric oxide (NO). These levels are hypothesized to reflect the degree of airway inflammation …
Neutrophilic infiltration within the airway smooth muscle in patients with COPD
S Baraldo, G Turato, C Badin, E Bazzan, B Beghe… - Thorax, 2004 - thorax.bmj.com
Background: COPD is an inflammatory disorder characterised by chronic airflow limitation,
but the extent to which airway inflammation is related to functional abnormalities is still …
but the extent to which airway inflammation is related to functional abnormalities is still …
Nonasthmatic chronic cough: No effect of treatment with an inhaled corticosteriod in patients without sputum eosinophilia
MMM Pizzichini, E Pizzichini… - Canadian respiratory …, 1999 - hindawi.com
BACKGROUND: Inhaled corticosteroids are effective in suppressing a chronic cough without
asthma associated with sputum eosinophilia. OBJECTIVE: To investigate the inflammatory …
asthma associated with sputum eosinophilia. OBJECTIVE: To investigate the inflammatory …