Identification of Chromosomal Genes in Yersinia pestis that Influence Type III Secretion and Delivery of Yops into Target Cells

AS Houppert, E Kwiatkowski, EM Glass, KL DeBord… - PLoS …, 2012 - journals.plos.org
Pathogenic Yersinia species possess a type III secretion system, which is required for the
delivery of effector Yop proteins into target cells during infection. Genes encoding the type III …

Transmission Factors: Yersinia pestis Genes Required to Infect the Flea Vector of Plague

BJ Hinnebusch - The genus Yersinia: entering the functional genomic …, 2003 - Springer
Conclusion Y. pestis Ymt and Hms proteins have complementary but distinct roles. Ymt is
required for survival in the midgut compartment, but not the proventriculus compartment, of …

Identification of In Vivo-Induced Conserved Sequences from Yersinia pestis During Experimental Plague Infection in the Rabbit

GP Andrews, G Vernati, R Ulrich, TE Rocke… - Vector-Borne and …, 2010 - liebertpub.com
In an effort to identify the novel virulence determinants of Yersinia pestis, we applied the
gene “discovery” methodology, in vivo-induced (IVI) antigen technology, to detect genes …

Analysis of Yersinia pestis gene expression in the flea vector

V Vadyvaloo, F Sebbane, BJ Hinnebusch… - The Genus Yersinia …, 2007 - Springer
Yersinia pestis is the causative agent of plague. Unlike the other pathogenic Yersinia
species, Y. pestis has evolved an arthropod-borne route of transmission, alternately infecting …

The smpB-ssrA Mutant of Yersinia pestis Functions as a Live Attenuated Vaccine To Protect Mice against Pulmonary Plague Infection

NA Okan, P Mena, JL Benach, JB Bliska… - Infection and …, 2010 - Am Soc Microbiol
ABSTRACT The bacterial SmpB-SsrA system is a highly conserved translational quality
control mechanism that helps maintain the translational machinery at full capacity. Here we …

Yersinia pestis and plague

RW Titball, J Hill, DG Lawton… - Biochemical Society …, 2003 - portlandpress.com
Yersinia pestis is the aetiological agent of plague, a disease of humans that has potentially
devastating consequences. Evidence indicates that Y. pestis evolved from Yersinia …

YopP-Expressing Variant of Y. pestis Activates a Potent Innate Immune Response Affording Cross-Protection against Yersiniosis and Tularemia

A Zauberman, Y Flashner, Y Levy, Y Vagima, A Tidhar… - PloS one, 2013 - journals.plos.org
Plague, initiated by Yersinia pestis infection, is a rapidly progressing disease with a high
mortality rate if not quickly treated. The existence of antibiotic-resistant Y. pestis strains …

Yersinia pestis Live Vaccine with improved characteristics

VA Feodorova, LN Pan'kina, EP Savostina… - Procedia in …, 2009 - Elsevier
The live plague vaccine strain Y. pestis EV line NIIEG widely used for human and animal
immunisation proves a high level of specific immunity against both bubonic and pneumonic …

Genotyping of a Homogeneous Group of Yersinia pestis Strains Isolated in the United States

XZ Huang, MC Chu, DM Engelthaler… - Journal of clinical …, 2002 - Am Soc Microbiol
Yersinia pestis, the causative agent of deadly plague, is considered a reemerging infectious
disease and a significant biological terrorism threat. The present project focused on …

In vivo comparison of avirulent Vwa-and Pgm-or Pstr phenotypes of yersiniae

T Une, RR Brubaker - Infection and immunity, 1984 - Am Soc Microbiol
The abilities of Yersinia pestis to undergo restriction in Ca2+-deficient medium with
concomitant production of V and W antigens (Vwa+) and to absorb exogenous pigments …