Childhood maltreatment (CM) is all too frequent among western societies, with an estimated
prevalence of 10 to 15%. CM associates with increased risk of several psychiatric disorders …

Childhood maltreatment (CM) has estimated prevalence among Western societies between
10% and 15%. As CM associates with increased risk of several psychiatric disorders, early …

Childhood maltreatment is a major risk factor for chronic and severe mental and physical
health problems across the lifespan. Increasing evidence supports the hypothesis that …

Epigenetic modification, such as DNA methylation (DNAm), is a mechanism that can help
explain how early adversities can engender long-term vulnerability for mental health …

Experiences during early development profoundly affect development of the central nervous
system (CNS) to impart either risk for or resilience to later psychopathology. Work in the …

DNA methylation (DNAm)–an epigenetic process that regulates gene expression–may
represent a mechanism for the biological embedding of early traumatic experiences …

It has long been recognized that early adversity can have life‐long consequences, and the
extent to which this is true is gaining increasing attention. A growing body of literature …

Childhood maltreatment is a key risk factor for poor mental and physical health. Recently,
variation in epigenetic processes, such as DNA methylation, has emerged as a potential …

Prospective studies suggest that child maltreatment substantially increases the risk for
depression in adulthood. However, the mechanisms underlying this association require …

Childhood adversity affects later health, but the underlying molecular mechanisms are
unclear. Although there is some evidence from animal models and case-control studies of a …