Metastases to central nervous system (CNS) are very common in nonsmall cell lung cancer
(NSCLC) patients with epidermal growth factor receptor (EGFR)-positive mutation. Brain is …

Central nervous system (CNS) metastases are a frequent and severe complication
associated with epidermal growth factor receptor (EGFR)-mutated non-small cell lung …

Brain metastases are usual in non-small-cell lung cancer (NSCLC) with poor prognosis and
few available therapeutic options. This retrospective study aims to evaluate the efficacy of …

Non-small cell lung cancer (NSCLC) continues to be one of the major causes of cancer-
related deaths worldwide, and brain metastases are the major cause of death in NSCLC …

Lung cancer is one of the major causes of cancer related mortality worldwide. Brain
metastases (BM) complicate clinical evolution of non-small cell lung cancer (NSCLC) in …

Background Patients with activating epidermal growth factor receptor (EGFR) mutations are
highly responsive to EGFR-tyrosine kinase inhibitors (TKIs). However, it has been reported …

Brain metastases and/or leptomeningeal disease (LMD) with associated central nervous
system (CNS) metastases are known complications of advanced epidermal growth factor …

Background Compared with standard chemotherapy, epidermal growth factor receptor
tyrosine kinase inhibitors (EGFR-TKIs) are more effective in patients with advanced non …

ABSTRACT Background About 30–40% of all patients (pts) with NSCLC develop BM,
leading to a poor prognosis and a median survival of< 6 months after whole brain …

A considerable proportion of non-small-cell lung cancer (NSCLC) patients will develop
central nervous system (CNS) metastases throughout the course of their disease and these …