Vitexin, a lignan compound, has been shown to exert apoptotic actions on human breast
cancer cell lines and to have anti-inflammatory activities. Nevertheless, there is currently no …

Background Currently, the prognosis of patients with non-small cell lung cancer (NSCLC)
remains dismal; hence, it is critical to identify effective anti-NSCLC agents with limited side …

Previous studies have reported that vitexins induce cytotoxic effects. In the present study, we
investigate a new native lignan vitexin 6 (VB6) in vitro to determine the molecular …

Purpose: Lignans such as secoisolariciresinol diglucoside in flaxseed, are metabolizes to
bioactive mammalian lignans of END and ENL. Because mammalian lignans have chemical …

Glioblastoma is a common primary brain tumor with aggressive malignancy, which results in
poor outcomes, short survival time and high mortality. Vitexin, an active ingredient from …

Aim To investigate the inhibitory effect of vitexicarpin on the proliferation of human cancer
cells and its mechanism of action. Methods The inhibitory effect of vitexicarpin on the …

Objective In our previous study, we had isolated a series of lignan compounds, termed
vitexins, from the seed of Chinese herb Vitex negundo and found broad antitumor activities …

Vitexin, a flavonoids compound, is known to exhibit broad anti-oxidative, anti-inflammatory,
analgesic, and antitumor activity in many cancer xenograft models and cell lines. The …

Cancer is a primary public health problem and the second leading cause of death
worldwide. It causes life‐threatening malignancies and results in high financial costs for both …

Abstract Purified vitexin compound 1 (VB1, a neolignan isolated and extracted from the seed
of Chinese herb Vitex negundo) is an effective antitumor agent and exhibits promising …