A common occurrence in metazoan development is the rise of multiple tissues/organs from a
single uniform precursor field. One example is the anterior forebrain of vertebrates, which …

The eye-antennal disc of Drosophila gives rise to numerous adult tissues, including the
compound eyes, ocelli, antennae, maxillary palps and surrounding head capsule. The fate …

A general question in development is how do adjacent primordia adopt different
developmental fates and stably maintain their distinct fates? In Drosophila melanogaster, the …

The eye–antennal disc of Drosophila is serving a guiding role in the studies of how eye
identity is specified, as well as how the retina is patterned. However, this system also holds a …

Abstract The Decapentaplegic and Notch signaling pathways are thought to direct regional
specification in the Drosophila eye-antennal epithelium by controlling the expression of …

In Drosophila, the eye and antenna originate from a single epithelium termed the eye-
antennal imaginal disc. Illumination of the mechanisms that subdivide this epithelium into …

Size trade-offs of visual versus olfactory organs is a pervasive feature of animal evolution.
This could result from genetic or functional constraints. We demonstrate that head sensory …

The formation of different structures in Drosophila depends on the combined activities of
selector genes and signaling pathways. For instance, the antenna requires the selector …

In the early Drosophila embryo, a system of coordinates is laid down by segmentation genes
and dorsoventral patterning genes. Subsequently, these coordinates must be interpreted to …

How multifunctional signals combine to specify unique cell fates during pattern formation is
not well understood. Here, we demonstrate that together with the transcription factor …