Role of medial prefrontal and orbitofrontal monoamine transporters and receptors in performance in an adjusting delay discounting procedure

JR Yates, JL Perry, AC Meyer, CD Gipson, R Charnigo… - Brain Research, 2014 - Elsevier
Performance in an adjusting delay discounting procedure is predictive of drug abuse
vulnerability; however, the shared underlying specific prefrontal neural systems linking delay …

Frontoparietal cortical activity of methamphetamine‐dependent and comparison subjects performing a delay discounting task

JR Monterosso, G Ainslie, J Xu, X Cordova… - Human brain …, 2007 - Wiley Online Library
Relative to individuals who do not have addictive disorders, drug abusers exhibit greater
devaluation of rewards as a function of their delay (“delay discounting”). The present study …

Partial inactivation of nucleus accumbens core decreases delay discounting in rats without affecting sensitivity to delay or magnitude

TM Moschak, SH Mitchell - Behavioural brain research, 2014 - Elsevier
Increased preference for smaller, sooner rewards (delay discounting) is associated with
several behavioral disorders, including ADHD and substance use disorders. However, delay …

Cortical activation during delay discounting in abstinent methamphetamine dependent individuals

WF Hoffman, DL Schwartz, MS Huckans… - …, 2008 - Springer
Background Methamphetamine (MA)-dependent individuals prefer smaller immediate over
larger delayed rewards in delay discounting (DD) tasks. Human and animal data implicate …

Decision making: effects of methylphenidate on temporal discounting in nonhuman primates

AZ Rajala, RL Jenison, LC Populin - 2015 - journals.physiology.org
Decisions are often made based on which option will result in the largest reward. When
given a choice between a smaller but immediate reward and a larger delayed reward …

Role of serotonin transporter function in rat orbitofrontal cortex in impulsive choice

M Darna, JJ Chow, JR Yates, RJ Charnigo… - Behavioural brain …, 2015 - Elsevier
Impulsivity is a multi-faceted personality construct that plays a prominent role in drug abuse
vulnerability. Dysregulation of 5-hydroxytryptamine (serotonin, 5-HT) systems in subregions …

Impulsive rats exhibit blunted dopamine release dynamics during a delay discounting task independent of cocaine history

TM Moschak, RM Carelli - ENeuro, 2017 - eneuro.org
The inability to wait for a large, delayed reward when faced with a small, immediate one,
known as delay discounting, has been implicated in a number of disorders including …

Preference reversals and effects of D-amphetamine on delay discounting in rats

CA Krebs, KG Anderson - Behavioural pharmacology, 2012 - journals.lww.com
Impulsive choice is correlated with behavioral problems such as attention-
deficit/hyperactivity disorder and substance abuse. Effects of stimulant drug administration …

Impaired DRL 30 performance during amphetamine withdrawal

JD Peterson, ME Wolf, FJ White - Behavioural brain research, 2003 - Elsevier
Repeated administration of psychomotor stimulants may produce an impulsive state that
could contribute to the cycle of drug abstinence and relapse seen in human drug addicts …

Ventral medial prefrontal cortex inactivation impairs impulse control but does not affect delay-discounting in rats

M Feja, M Koch - Behavioural brain research, 2014 - Elsevier
Maladaptive levels of impulsivity are found in several neuropsychiatric disorders, such as
ADHD, addiction, aggression and schizophrenia. Intolerance to delay-of-gratification, or …