Role of medial prefrontal and orbitofrontal monoamine transporters and receptors in performance in an adjusting delay discounting procedure
Performance in an adjusting delay discounting procedure is predictive of drug abuse
vulnerability; however, the shared underlying specific prefrontal neural systems linking delay …
vulnerability; however, the shared underlying specific prefrontal neural systems linking delay …
Frontoparietal cortical activity of methamphetamine‐dependent and comparison subjects performing a delay discounting task
JR Monterosso, G Ainslie, J Xu, X Cordova… - Human brain …, 2007 - Wiley Online Library
Relative to individuals who do not have addictive disorders, drug abusers exhibit greater
devaluation of rewards as a function of their delay (“delay discounting”). The present study …
devaluation of rewards as a function of their delay (“delay discounting”). The present study …
Partial inactivation of nucleus accumbens core decreases delay discounting in rats without affecting sensitivity to delay or magnitude
TM Moschak, SH Mitchell - Behavioural brain research, 2014 - Elsevier
Increased preference for smaller, sooner rewards (delay discounting) is associated with
several behavioral disorders, including ADHD and substance use disorders. However, delay …
several behavioral disorders, including ADHD and substance use disorders. However, delay …
Cortical activation during delay discounting in abstinent methamphetamine dependent individuals
WF Hoffman, DL Schwartz, MS Huckans… - …, 2008 - Springer
Background Methamphetamine (MA)-dependent individuals prefer smaller immediate over
larger delayed rewards in delay discounting (DD) tasks. Human and animal data implicate …
larger delayed rewards in delay discounting (DD) tasks. Human and animal data implicate …
Decision making: effects of methylphenidate on temporal discounting in nonhuman primates
AZ Rajala, RL Jenison, LC Populin - 2015 - journals.physiology.org
Decisions are often made based on which option will result in the largest reward. When
given a choice between a smaller but immediate reward and a larger delayed reward …
given a choice between a smaller but immediate reward and a larger delayed reward …
Role of serotonin transporter function in rat orbitofrontal cortex in impulsive choice
Impulsivity is a multi-faceted personality construct that plays a prominent role in drug abuse
vulnerability. Dysregulation of 5-hydroxytryptamine (serotonin, 5-HT) systems in subregions …
vulnerability. Dysregulation of 5-hydroxytryptamine (serotonin, 5-HT) systems in subregions …
Impulsive rats exhibit blunted dopamine release dynamics during a delay discounting task independent of cocaine history
TM Moschak, RM Carelli - ENeuro, 2017 - eneuro.org
The inability to wait for a large, delayed reward when faced with a small, immediate one,
known as delay discounting, has been implicated in a number of disorders including …
known as delay discounting, has been implicated in a number of disorders including …
Preference reversals and effects of D-amphetamine on delay discounting in rats
CA Krebs, KG Anderson - Behavioural pharmacology, 2012 - journals.lww.com
Impulsive choice is correlated with behavioral problems such as attention-
deficit/hyperactivity disorder and substance abuse. Effects of stimulant drug administration …
deficit/hyperactivity disorder and substance abuse. Effects of stimulant drug administration …
Impaired DRL 30 performance during amphetamine withdrawal
JD Peterson, ME Wolf, FJ White - Behavioural brain research, 2003 - Elsevier
Repeated administration of psychomotor stimulants may produce an impulsive state that
could contribute to the cycle of drug abstinence and relapse seen in human drug addicts …
could contribute to the cycle of drug abstinence and relapse seen in human drug addicts …
Ventral medial prefrontal cortex inactivation impairs impulse control but does not affect delay-discounting in rats
M Feja, M Koch - Behavioural brain research, 2014 - Elsevier
Maladaptive levels of impulsivity are found in several neuropsychiatric disorders, such as
ADHD, addiction, aggression and schizophrenia. Intolerance to delay-of-gratification, or …
ADHD, addiction, aggression and schizophrenia. Intolerance to delay-of-gratification, or …