Candida albicans is both a member of the healthy human microbiome and a major pathogen
in immunocompromised individuals. Infections are typically treated with azole inhibitors of …

Objectives The objective of this study was to characterize the underlying molecular
mechanisms in consecutive clinical Candida albicans isolates from a single patient …

Fungal infections, such as candidiasis caused by Candida, pose a problem of growing
medical concern. In developed countries, the incidence of Candida infections is increasing …

The evolution of drug resistance has a profound impact on human health. Candida glabrata
is a leading human fungal pathogen that can rapidly evolve resistance to echinocandins …

▪ Abstract The widespread deployment of antimicrobial agents in medicine and agriculture is
nearly always followed by the evolution of resistance to these agents in the pathogen. With …

Candida albicans is an opportunistic human fungal pathogen and a causative agent of
oropharyngeal candidiasis (OPC), the most frequent opportunistic infection among patients …

Both the incidence of invasive fungal infections and rates of multidrug resistance associated
with fungal pathogen Candida glabrata have increased in recent years. In this perspective …

Fungal infections are a major contributor to infectious disease-related deaths across the
globe. Candida species are among the most common causes of invasive mycotic disease …

Fungal pathogens use various mechanisms to survive exposure to drugs. Prolonged
treatment very often leads to the stepwise acquisition of resistance. The limited number of …

Fungal infections are a growing medical concern, in part due to increased resistance to one
or multiple antifungal drugs. However, the evolutionary processes underpinning the …