Chemotherapeutic agents with different anticancer mechanisms could enhance therapeutic
effect in cancer therapy by their combined application. In this study, redox-sensitive prodrug …

In the present study, novel pH-responsive prodrug nanoparticles based on xylan-curcumin
(xyl-cur) conjugate were developed to enhance the therapeutic efficacy of curcumin in …

Poor water solubility, short half-life, and low drug efficacy posed a challenge for clinical
application of curcumin (CUR). In this work, a kind of CUR prodrug was synthesized by …

Here, we prepared nano self-assembly of lysozyme via a directed optimized desolvation
process and conjugated it with an anticancer natural polyphenol, curcumin (Cur) onto the …

Ample attention has focused on cancer drug delivery via prodrug nanoparticles due to their
high drug loading property and comparatively lower side effects. In this study, we designed a …

Aim We designed acid-labile methotrexate (MTX) targeting prodrug self-assembling
nanoparticles loaded with curcumin (CUR) drug for simultaneous delivery of multi …

Tumor-responsive nanocarriers are highly valuable and demanded for smart anticancer
drug delivery, where a quick release of chemotherapeutic drugs in tumors is preferred …

The anti-tumor efficacy of curcumin can be markedly improved by nano-drug self-delivery
systems with high drug loading capacity and smart stimulus-triggered drug release in tumor …

Purpose A novel folate receptor-targeted β-cyclodextrin (β-CD) drug delivery vehicle was
constructed to improve the bioavailability, biosafety, and drug loading capacity of curcumin …

Nanoformulation of curcumin,(a low molecular weight hydrophobic drug) was prepared by
using dextran sulphate and chitosan. The developed nanoparticles were characterized by …