Purpose: Infantile spasms is one of the most severe epileptic syndromes of infancy and early
childhood. Progress toward understanding the pathophysiology of this disorder and the …

Infantile spasms is an unusual seizure disorder. The seizures themselves are only a few
seconds in duration and consist of brief flexion and/or extension jerking movements. EEG …

Purpose: To describe high frequency (HF) electrographic activity accompanying ictal
discharges in the tetrodotoxin (TTX) model of infantile spasms. Previous studies of HF …

Infantile spasms is an epilepsy syndrome with several distinctive features, including age
specificity during infancy, characteristic semiology (epileptic spasms), specific …

While infantile spasms is the most common catastrophic epilepsy of infancy and early-
childhood, very little is known about the basic mechanisms responsible for this devastating …

Purpose: To determine whether a new model of cryptogenic infantile spasms consisting of
prenatal priming with betamethasone and postnatal trigger of spasms by N‐methyl‐d …

Infantile spasms are the classical seizure type of West syndrome. Infantile spasms often
herald a dismal prognosis, due to the high probability to evolve into intractable forms of …

Infantile spasms are a devastating epileptic encephalopathy characterized by early life
spasms and later seizures. Clinical outcomes of infantile spasms are poor and therapeutic …

Infantile spasms are a seizure disorder in young infants with diverse etiologies, suggesting
that they arise from any disturbance of central nervous system function during susceptible …

Infantile spasms is one of the “catastrophic childhood epilepsies” because of the difficulty in
controlling seizures and the association with mental retardation. However, early recognition …