Role of peroxisome proliferator‑activated receptor α in atherosclerosis

H Cao, G Wen, H Li - Molecular Medicine Reports, 2014 - spandidos-publications.com
Atherosclerosis is an inflammatory disease involving the immune response. In addition to
lowering the cholesterol level, the peroxisome proliferator-activated receptor α (PPAR-α) can …

The expression and role of peroxisome proliferator-activated receptor α in atherosclerosis

W Gao, W Xu, H Li - Molecular medicine reports, 2013 - spandidos-publications.com
Peroxisome proliferator-activated receptor α (PPAR-α) has been detected in the liver,
kidney, heart and skeletal muscle. The expression and mechanism of PPAR-α in …

Role of the peroxisome proliferator-activated receptors (PPAR) in atherosclerosis

BP Neve, JC Fruchart, B Staels - Biochemical pharmacology, 2000 - Elsevier
Peroxisome proliferator-activated receptors (PPAR) are ligand-activated transcription factors
which form a subfamily of the nuclear receptor gene family. PPAR activators have effects on …

Expression of peroxisome proliferator‐activated receptor subtypes in human atherosclerosis

S Sueyoshi, T Yamada, M Niihasi… - Annals of the New …, 2001 - Wiley Online Library
To clarify the involvement of peroxisome proliferator‐activated receptors (PPARs) in
atherosclerotic plaque formation, we investigated the expression patterns of mRNA and …

The role of PPARs in atherosclerosis

C Duval, G Chinetti, F Trottein, JC Fruchart… - Trends in molecular …, 2002 - cell.com
Peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors
that regulate lipid and lipoprotein metabolism, glucose homeostasis and inflammation. The …

Macrophage Expression of Peroxisome Proliferator–Activated Receptor-α Reduces Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice

VR Babaev, H Ishiguro, L Ding, PG Yancey, DE Dove… - Circulation, 2007 - Am Heart Assoc
Background—The peroxisome proliferator–activated receptor-α (PPARα) plays important
roles in lipid metabolism, inflammation, and atherosclerosis. PPARα ligands have been …

Expression of the peroxisome proliferator-activated receptor γ (PPARγ) in human atherosclerosis and regulation in macrophages by colony stimulating factors and …

M Ricote, J Huang, L Fajas, A Li… - Proceedings of the …, 1998 - National Acad Sciences
The peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-dependent
transcription factor that has been demonstrated to regulate fat cell development and glucose …

Role of Peroxisome Proliferator‐Activated Receptor‐γ in Vascular Inflammation

K Ohshima, M Mogi, M Horiuchi - International journal of …, 2012 - Wiley Online Library
Vascular inflammation plays a crucial role in atherosclerosis, and its regulation is important
to prevent cerebrovascular and coronary artery disease. The inflammatory process in …

Peroxisome proliferator-activated receptor γ and atherosclerosis

N Marx - Current hypertension reports, 2002 - Springer
Within the past couple of years, peroxisome proliferator-activated receptor γ (PPARγ), a
nuclear transcription factor expressed in vascular cells, has received growing interest in …

Peroxisome proliferator-activated receptors in atherosclerosis and inflammation—an update

CS Elangbam, RD Tyler… - Toxicologic pathology, 2001 - journals.sagepub.com
Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor
subfamily of transcription factors with pleiotropic effects on intra-and extracellular lipid …