Identification of key target genes and biological pathways in multiple sclerosis brains using microarray data obtained from the Gene Expression Omnibus database
W Zheng, Y Chen, H Chen, W Xiao, YJ Liang… - Neurological …, 2018 - Taylor & Francis
Objective: The purpose of this study was to investigate critical genes in multiple sclerosis
(MS) using microarray data from brain tissue in MS. Materials: The expression profile data …
(MS) using microarray data from brain tissue in MS. Materials: The expression profile data …
Identification of Key Genes and Regulatory Pathways in Multiple Sclerosis Brain Samples: A Meta-Analysis of Micro-Array Datasets
MI Jansen, A Castorina - International Journal of Molecular Sciences, 2023 - mdpi.com
Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system (CNS)
whose aetiology is only partly understood. Investigating the intricate transcriptional changes …
whose aetiology is only partly understood. Investigating the intricate transcriptional changes …
Microarray gene expression profiling analysis combined with bioinformatics in multiple sclerosis
M Liu, X Hou, P Zhang, Y Hao, Y Yang, X Wu… - Molecular biology …, 2013 - Springer
Multiple sclerosis (MS) is the most prevalent demyelinating disease and the principal cause
of neurological disability in young adults. Recent microarray gene expression profiling …
of neurological disability in young adults. Recent microarray gene expression profiling …
Investigation of differentially expressed genes and dysregulated pathways involved in multiple sclerosis
Multiple Sclerosis (MS) is a neurodegenerative autoimmune and organ-specific
demyelinating disorder, known to affect the central nervous system (CNS). While genetic …
demyelinating disorder, known to affect the central nervous system (CNS). While genetic …
Network-based analysis of differentially expressed genes in cerebrospinal fluid (CSF) and blood reveals new candidate genes for multiple sclerosis
Background The involvement of multiple genes and missing heritability, which are dominant
in complex diseases such as multiple sclerosis (MS), entail using network biology to better …
in complex diseases such as multiple sclerosis (MS), entail using network biology to better …
Identification of key genes associated with multiple sclerosis based on gene expression data from peripheral blood mononuclear cells
Z Shang, W Sun, M Zhang, L Xu, X Jia, R Zhang, S Fu - PeerJ, 2020 - peerj.com
The aim of this study was to identify the potential key candidate genes of multiple sclerosis
(MS) and uncover mechanisms in MS. We combined data from the microarray expression …
(MS) and uncover mechanisms in MS. We combined data from the microarray expression …
Gene expression profiling in multiple sclerosis brain
R Dutta, BD Trapp - Neurobiology of disease, 2012 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system and the leading cause of non-traumatic neurological disability in young …
nervous system and the leading cause of non-traumatic neurological disability in young …
Dense module searching for gene networks associated with multiple sclerosis
Background Multiple sclerosis (MS) is a complex disease in which the immune system
attacks the central nervous system. The molecular mechanisms contributing to the etiology …
attacks the central nervous system. The molecular mechanisms contributing to the etiology …
Identification of blood-derived candidate gene markers and a new 7-gene diagnostic model for multiple sclerosis
X Chen, H Hou, H Qiao, H Fan, T Zhao, M Dong - Biological Research, 2021 - Springer
Background Multiple sclerosis (MS) is a central nervous system disease with a high
disability rate. Modern molecular biology techniques have identified a number of key genes …
disability rate. Modern molecular biology techniques have identified a number of key genes …
[HTML][HTML] cDNA microarray and bioinformatic analysis for the identification of key genes in Alzheimer's disease
C Gu, T Shen - International Journal of Molecular …, 2014 - spandidos-publications.com
In this study, gene expression profiles in peripheral blood monocytes from patients with
Alzheimer's disease (AD) or mild cognitive impairment (MCI) were compared with those of …
Alzheimer's disease (AD) or mild cognitive impairment (MCI) were compared with those of …