Background B-lymphoma Moloney murine leukemia virus insertion region-1 (Bmi-1) acts as
an oncogene in various tumors, and its overexpression correlates with a poor outcome in …

Ovarian cancer is the fourth most common cause of cancer-related death in women. Bmi-1 is
a stem cell factor implicated in many human malignancies with poor outcome. Few …

Bmi-1, a member of the polycomb family, it is involved in self renewal of stem cells and
functions as an oncogene in many malignant human cancer types. Recent studies have …

The Bmi-1 oncogene is overexpressed in a number of malignancies including breast cancer.
In addition to Bmi-1, mammalian cells also express four other polycomb group (PcG) …

Bmi-1, a polycomb gene family member, plays an important role in cell cycle regulation, cell
immortalization, and cell senescence. Recently, numerous studies have demonstrated that …

Oncogenic activation of Bmi-1 is found in a wide variety of epithelial malignancies including
ovarian cancer, yet a specific mechanism for overexpression of Bmi-1 has not been …

Expression of Bmi-1 in gallbladder carcinoma and its clinicopathology and mechanisms of
regulation of human gallbladder carcinoma cell proliferation were investigated. Fifty cases of …

Background Bmi1, a polycomb group gene, is essential for self-renewal of stem cells and is
frequently upregulated in various cancer cells. We aimed to investigate the effect of Bmi1 …

We report here that the polycomb group protein Bmi1 promotes prostate tumorigenesis.
Bmi1 is detected at higher levels in androgen-independent PC3 and DU145 than in …

Background: Oncogenic Bmi-1 (B-lymphoma Moloney murine leukemia virus insertion
region-1) belongs to the Polycomb-group (PcG) family of proteins and plays an important …