To clarify the roles of Bmi-1 in colorectal carcinoma, we examined the expression of Bmi-1 in
41 samples out of 46 colorectal carcinomas by reverse transcription-PCR, whereas all 46 …

Background It has been suggested that the B-cell specific moloney leukemia virus insertion
site 1 (Bmi-1) gene plays an oncogenic role in several types of human cancer, but the status …

Background The molecular mechanisms of the development and progression of bladder
cancer are poorly understood. The objective of this study was to analyze the expression of …

Bmi1 is overexpressed in gastrointestinal cancers, including colorectal cancer (CRC);
however, its role as a non‑invasive biomarker in CRC has not been established. The aim of …

Abstract Background and Objective The Bmi‐1 gene is a transcriptional repressor involved
in oncogenesis in various human cancers. Here, we examine Bmi‐1 expression in gastric …

Deregulation of the polycomb group gene BMI-1 is implicated in the pathogenesis of many
human cancers. In this study, we have investigated if the Ewing sarcoma family of tumors …

Abstract Background The Polycomb group (PcG) genes are a class of regulators responsible
for maintaining homeotic gene expression throughout cell division. PcG expression is …

Expression of Bmi-1 in gallbladder carcinoma and its clinicopathology and mechanisms of
regulation of human gallbladder carcinoma cell proliferation were investigated. Fifty cases of …

Bmi‐1 is overexpressed in uterine cervical cancer (UCC) and is found to be associated with
adverse clinical characteristics and poor prognosis. However, little information is available …

Recently, BMI-1 was identified as a protein downregulating p16ink4a and mandatory for the
continued existence of several stem cell compartments like hematopoietic and neural stem …