Angiotensin-converting enzyme (ACE) 2 is a recently identified homologue of ACE. There is
great interest in the therapeutic benefit for ACE2 overexpression in the heart. However, the …

Background Angiotensin‐converting enzyme 3 (ACE 3) is a recently defined homolog of
ACE. However, the pathophysiological function of ACE 3 is largely unknown. Here, we aim …

Cardiac remodelling is a key risk factor for the development of heart failure in the chronic
phase following myocardial infarction. Our previous studies have shown an anti-remodelling …

The renin–angiotensin system (RAS), in particular angiotensin II, plays an important role in
cardiac remodelling. Angiotensin‐converting enzyme (ACE) and angiotensin‐converting …

Angiotensin converting enzyme 2 (ACE2) has been linked to cardiac dysfunction and
hypertension-induced cardiac pathophysiology. In this study, we used a gene …

Abstract Angiotensin-converting enzyme 2 (ACE2) metabolizes Ang II into Ang 1–7 thereby
negatively regulating the renin-angiotensin system. However, heart disease in humans and …

In order to investigate the role of angiotensin-converting enzyme 2 (ACE2) in cardiac
development, we examined the effects of ACE2 deficiency on postnatal development of the …

It has been reported that angiotensin converting enzyme (ACE) 2, a homologue of ACE, has
direct effects on cardiac function. However, the role of ACE2 in the development of human …

Angiotensin-converting enzyme 2 (ACE2) is present in the heart and thought to exert
protective functions. We conducted studies in ACE2 deficient mice to determine whether …

Increased cardiac angiotensin converting enzyme-1 (ACE1) is found in individuals who
carry a deletion in intron 16 of ACE1 gene or in individuals who suffer from cardiac …