Accumulating evidence suggests that AMP-activated protein kinase (AMPK) activation exerts
anti-apoptotic effects in multiple types of cells. However, the underlying mechanisms remain …

The inhibition of apoptotic changes in vascular endothelial cells is important for preventing
vascular damage from hypoxia. AMP-activated protein kinase (AMPK) has recently been …

AMP-activated protein kinase (AMPK) is an evolutionary conserved energy-sensing enzyme
that regulates cell metabolism. Emerging evidence indicates that AMPK also plays an …

Background In endothelial cells, activation of the AMP-activated protein kinase (AMPK) has
been linked with anti-inflammatory actions but the events downstream of kinase activation …

The role of p38 mitogen-activated protein kinase (MAPK) in apoptosis is a matter of debate.
Here, we investigated the involvement of p38 MAPK in endothelial apoptosis induced by …

AMP-activated protein kinase (AMPK) is a stress-activated protein kinase that is regulated by
hypoxia and other cellular stresses that result in diminished cellular ATP levels. Here, we …

Apoptosis plays an indispensable role in the maintenance and development of tissues. We
have shown that receptor-mediated recognition of apoptotic target cells by viable kidney …

Rationale: The AMP-activated protein kinase (AMPK) is stimulated by hypoxia, and although
the AMPKα1 catalytic subunit has been implicated in angiogenesis, little is known about the …

The inhibitor of apoptosis protein (IAP) family of molecules regulates apoptotic processes
triggered by various stimuli. However, the mechanisms involved in the regulation of the IAP …

Monocyte-to-macrophage differentiation, which can be initiated by physiological or
atherogenic factors, is a pivotal process in atherogenesis, a disorder in which monocytes …