BAFF: a local and systemic target in autoimmune diseases
I Moisini, A Davidson - Clinical & Experimental Immunology, 2009 - academic.oup.com
BAFF (B lymphocyte activating factor of the tumour necrosis factor family) is a vital
homeostatic cytokine for B cells that helps regulate both innate and adaptive immune …
homeostatic cytokine for B cells that helps regulate both innate and adaptive immune …
The role of BAFF in immune function and implications for autoimmunity
SL Kalled - Immunological reviews, 2005 - Wiley Online Library
BAFF [B‐cell activating factor belonging to the tumor necrosis factor (TNF) family] is a ligand
that is required for peripheral B‐cell survival and homeostasis. In addition to mediating B …
that is required for peripheral B‐cell survival and homeostasis. In addition to mediating B …
Targeting BAFF in autoimmunity
A Davidson - Current opinion in immunology, 2010 - Elsevier
BAFF and APRIL are TNF-like cytokines that support survival and differentiation of B cells.
The early appreciation that overexpression of BAFF leads to B cell expansion and a lupus …
The early appreciation that overexpression of BAFF leads to B cell expansion and a lupus …
Cracking the BAFF code
F Mackay, P Schneider - Nature reviews immunology, 2009 - nature.com
The tumour necrosis factor (TNF) family members B cell activating factor (BAFF) and APRIL
(a proliferation-inducing ligand) are crucial survival factors for peripheral B cells. An excess …
(a proliferation-inducing ligand) are crucial survival factors for peripheral B cells. An excess …
Targeting BAFF: immunomodulation for autoimmune diseases and lymphomas
APR Sutherland, F Mackay, CR Mackay - Pharmacology & therapeutics, 2006 - Elsevier
In an effort to develop more effective treatments for inflammatory diseases, immunologists
have targeted numerous molecular pathways, but with limited success. Notable exceptions …
have targeted numerous molecular pathways, but with limited success. Notable exceptions …
BAFF inhibition: a new class of drugs for the treatment of autoimmunity
Z Liu, A Davidson - Experimental cell research, 2011 - Elsevier
BAFF (BLyS) and APRIL are TNF-like cytokines that support survival and differentiation of B
cells. Recent studies have discovered a role for BAFF in augmenting both innate and …
cells. Recent studies have discovered a role for BAFF in augmenting both innate and …
BAFF and the regulation of B cell survival
P Schneider, J Tschopp - Immunology letters, 2003 - Elsevier
The TNF family member BAFF is a fundamental survival factor for B cells. BAFF binds to
three receptors, only one of which, BAFF-R, does not cross-react with the BAFF-related …
three receptors, only one of which, BAFF-R, does not cross-react with the BAFF-related …
BAFF: a fundamental survival factor for B cells
F Mackay, JL Browning - Nature Reviews Immunology, 2002 - nature.com
B-cell-activating factor of the tumour-necrosis-factor family (BAFF) enhances B-cell survival—
a function that is indispensable for B-cell maturation—and has a role in enhancing immune …
a function that is indispensable for B-cell maturation—and has a role in enhancing immune …
BAFF, APRIL and human B cell disorders
B cells require signals from multiple sources for their development from precursor cells, and
differentiation into effector cells. BAFF has been identified as a critical regulator of B cell …
differentiation into effector cells. BAFF has been identified as a critical regulator of B cell …
The function of BAFF on T helper cells in autoimmunity
M Chen, X Lin, Y Liu, Q Li, Y Deng, Z Liu… - Cytokine & growth factor …, 2014 - Elsevier
B cell-activating factor belonging to the TNF family (BAFF) exerts its pathogenic role in
supporting the survival and proliferation of B cells, regulating class switch recombination as …
supporting the survival and proliferation of B cells, regulating class switch recombination as …