Cadmium induced testicular pathophysiology: prophylactic role of taurine

P Manna, M Sinha, PC Sil - Reproductive toxicology, 2008 - Elsevier
The aim of the present study was to investigate the role of taurine against cadmium induced
testicular pathophysiology. Cadmium (in the form of Cadmium chloride, CdCl2) …

Cadmium-induced activation of stress signaling pathways, disruption of ubiquitin-dependent protein degradation and apoptosis in primary rat Sertoli cell-gonocyte …

X Yu, S Hong, EM Faustman - Toxicological sciences, 2008 - academic.oup.com
Cadmium (Cd) is a ubiquitous environmental pollutant that has been associated with male
reproductive toxicity in both humans and animal models. The underlying mechanism of this …

Comprehensive review of cadmium toxicity mechanisms in male reproduction and therapeutic strategies

L Xiong, B Zhou, H Liu, L Cai - Reviews of Environmental Contamination …, 2021 - Springer
Cadmium (Cd) has been widely studied as an environmental pollutant for many years.
Numerous studies have reported that Cd exposure causes damage to the heart, liver …

Excess iodine impairs spermatogenesis by inducing oxidative stress and perturbing the blood testis barrier

A Chakraborty, V Singh, K Singh, S Rajender - Reproductive Toxicology, 2020 - Elsevier
Approximately 2 billion people worldwide are susceptible to iodine deficiency. Iodine
deficiency has largely been tackled by iodine fortification in salt; however indiscriminate use …

Signaling proteins that regulate spermatogenesis are the emerging target of toxicant-induced male reproductive dysfunction

S Gao, X Wu, L Wang, T Bu, A Perrotta… - Frontiers in …, 2021 - frontiersin.org
There is emerging evidence that environmental toxicants, in particular endocrine disrupting
chemicals (EDCs) such as cadmium and perfluorooctanesulfonate (PFOS), induce Sertoli …

Altered expression of DAAM1 and PREP induced by cadmium toxicity is counteracted by melatonin in the rat testis

M Venditti, M Ben Rhouma, MZ Romano, I Messaoudi… - Genes, 2021 - mdpi.com
Cadmium (Cd) is one of the most toxic pollutants for health due to its accumulation in several
tissues, including testis. This report confirms that Cd increased oxidative stress and …

Aucubin supplementation alleviate diabetes induced-disruption of blood-testis barrier and testicular damage via stabilizing cell junction integrity

J Wei, X Lu, X Bao, C Zhang, J Li, C Ren, Z Zhu… - European Journal of …, 2023 - Elsevier
Disruption of blood-testis barrier (BTB) was a crucial pathological feature of diabetes
induced-testicular injury at early phase. Aucubin (AU), a main active component in …

Mechanisms of diazinon effects on impaired spermatogenesis and male infertility

AB Harchegani, A Rahmani… - Toxicology and …, 2018 - journals.sagepub.com
Diazinon (DZN) is an organophosphate insecticide that has cytotoxic and pathological
effects on the reproductive system. It causes a wide variety of pathological effects on the …

Aucubin, a natural iridoid glucoside, attenuates oxidative stress-induced testis injury by inhibiting JNK and CHOP activation via Nrf2 up-regulation

B Ma, J Zhang, Z Zhu, X Bao, M Zhang, C Ren… - Phytomedicine, 2019 - Elsevier
Background Eucommia ulmoides has been used for many years as a successful strategy to
treat male infertility. Aucubin (AU) is the active ingredient extracted from Eucommia …

[PDF][PDF] Protective effect of alpha-tocopheral on biochemical and histological alterations induced by cadmium in rat testes

B Rajendar, K Bharavi, GS Rao… - Indian J Physiol …, 2011 - researchgate.net
Abstract: Cadmium (Cd) is a potential environmental pollutant and causes severe damage to
reproductive organs in adults including ovary and testes. Of all antioxidants α-tocopheral is …