Burkholderia cenocepacia Differential Gene Expression during Host–Pathogen Interactions and Adaptation to the Host Environment

EP O'Grady, PA Sokol - Frontiers in Cellular and Infection …, 2011 - frontiersin.org
Members of the Burkholderia cepacia complex (Bcc) are important in medical,
biotechnological, and agricultural disciplines. These bacteria naturally occur in soil and …

Burkholderia cepacia Complex Regulation of Virulence Gene Expression: A Review

SA Sousa, JR Feliciano, T Pita, SI Guerreiro, JH Leitão - Genes, 2017 - mdpi.com
Burkholderia cepacia complex (Bcc) bacteria emerged as opportunistic pathogens in cystic
fibrosis and immunocompromised patients. Their eradication is very difficult due to the high …

Identification of Potential Therapeutic Targets for Burkholderia cenocepacia by Comparative Transcriptomics

DR Yoder-Himes, KT Konstantinidis, JM Tiedje - PLoS One, 2010 - journals.plos.org
Background Burkholderia cenocepacia is an endemic soil dweller and emerging
opportunistic pathogen in patients with cystic fibrosis (CF). The identification of virulence …

Global changes in gene expression by the opportunistic pathogen Burkholderia cenocepacia in response to internalization by murine macrophages

JS Tolman, MA Valvano - BMC genomics, 2012 - Springer
Background Burkholderia cenocepacia is an opportunistic pathogen causing life-threatening
infections in patients with cystic fibrosis. The bacterium survives within macrophages by …

Phase variation has a role in Burkholderia ambifaria niche adaptation

L Vial, MC Groleau, MG Lamarche, G Filion… - The ISME …, 2010 - academic.oup.com
Members of the Burkholderia cepacia complex (Bcc), such as B. ambifaria, are effective
biocontrol strains, for instance, as plant growth-promoting bacteria; however, Bcc isolates …

Proteomic identification and characterization of bacterial factors associated with Burkholderia cenocepacia survival in a murine host

JW Chung, DP Speert - Microbiology, 2007 - microbiologyresearch.org
Burkholderia cenocepacia is a member of the Burkholderia cepacia complex, a diverse
family of Gram-negative bacteria that are serious respiratory pathogens in …

The unexpected discovery of a novel low-oxygen-activated locus for the anoxic persistence of Burkholderia cenocepacia

AM Sass, C Schmerk, K Agnoli, PJ Norville… - The ISME …, 2013 - academic.oup.com
Burkholderia cenocepacia is a Gram-negative aerobic bacterium that belongs to a group of
opportunistic pathogens displaying diverse environmental and pathogenic lifestyles. B …

Genomic Expression Analysis Reveals Strategies of Burkholderia cenocepacia to Adapt to Cystic Fibrosis Patients' Airways and Antimicrobial Therapy

NP Mira, A Madeira, AS Moreira, CP Coutinho… - PLoS …, 2011 - journals.plos.org
Pulmonary colonization of cystic fibrosis (CF) patients with Burkholderia cenocepacia or
other bacteria of the Burkholderia cepacia complex (Bcc) is associated with worse prognosis …

Identification of Specific and Universal Virulence Factors in Burkholderia cenocepacia Strains by Using Multiple Infection Hosts

S Uehlinger, S Schwager, SP Bernier… - Infection and …, 2009 - Am Soc Microbiol
Over the past few decades, strains of the Burkholderia cepacia complex have emerged as
important pathogens for patients suffering from cystic fibrosis. Identification of virulence …

Identification of Burkholderia cenocepacia Genes Required for Bacterial Survival In Vivo

TA Hunt, C Kooi, PA Sokol, MA Valvano - Infection and immunity, 2004 - Am Soc Microbiol
Burkholderia cenocepacia (formerly Burkholderia cepacia complex genomovar III) causes
chronic lung infections in patients with cystic fibrosis. In this work, we used a modified …