Alzheimer's disease, an age-related neurodegenerative disorder, is characterized clinically
by a progressive loss of memory and cognitive functions. Neuropathologically, Alzheimer's …

Aging is the major risk factor associated with neurodegenerative diseases, including
Alzheimer's disease (AD). Until now no clear understanding of the mechanisms of initiation …

Alzheimer's disease (AD), the leading cause of dementia, involves regionalized neuronal
death, synaptic loss, and an accumulation of intraneuronal, neurofibrillary tangles and …

Alzheimer's disease is a progressive neurodegenerative disease associated with loss of
memory and cognition. One hallmark of AD is the accumulation of amyloid β-peptide (Aβ) …

Alzheimer disease is a common age-related neurodegenerative disease characterized
pathologically by senile plaques, neurofibrillary tangles, synaptic disruption, and …

Accumulation of oxidative damage is a common feature of neurodegeneration that, together
with mitochondrial dysfunction, point to the fact that reactive oxygen species are major …

Several studies demonstrated that oxidative damage is a characteristic feature of many
neurodegenerative diseases. The accumulation of oxidatively modified proteins may disrupt …

In Alzheimer's disease (AD) brain oxidative stress is observed indexed by several markers,
among which are protein carbonyls and 3-nitrotyrosine, markers for protein oxidation. We …

Oxidative stress has been implicated to play a crucial role in the pathogenesis of a number
of diseases, including neurodegenerative disorders, cancer, and ischemia, just to name a …

Oxidative stress has been implicated in the pathogenesis of a number of diseases including
Alzheimer's disease (AD). The oxidative stress hypothesis of AD pathogenesis, in part, is …