Management of multisystem inflammatory syndrome in children: decision-making regarding a new condition in the absence of clinical trial data

AS Harahsheh, MA Portman, M Khoury… - Canadian Journal of …, 2023 - Elsevier
Multisystem inflammatory syndrome in children (MIS-C) is a new illness that evolved during
the COVID-19 pandemic with initial reports of severe disease including use of …

Management of multisystem inflammatory syndrome in children associated with COVID-19 infection

PN Jone, MD Everitt - Current Treatment Options in Pediatrics, 2021 - Springer
Purpose of review The purpose of this review is to summarize what is known about
multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19 infection …

Update on the treatment of multisystem inflammatory syndrome in children associated with COVID-19

F Long, S Zhu, Z Wang, S Zhang, J He, X Ge… - Future Virology, 2023 - Taylor & Francis
In late 2019, SARS-CoV-2 was detected in China and spread worldwide. In rare cases,
children who were infected with COVID-19 may develop multisystem inflammatory syndrome …

Presentation, treatment response and short-term outcomes in paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 (PIMS-TS)

S Felsenstein, E Willis, H Lythgoe, L McCann… - Journal of clinical …, 2020 - mdpi.com
The novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the
pathogen responsible for Coronavirus Disease 2019 (COVID-19). Whilst most children and …

Early combination therapy with immunoglobulin and steroids is associated with shorter ICU length of stay in Multisystem Inflammatory Syndrome in Children (MIS‐C) …

AA Harthan, M Nadiger, JS McGarvey… - … : The Journal of …, 2022 - Wiley Online Library
Objectives Suggested therapeutic options for Multisystem Inflammatory Syndrome in
Children (MIS‐C) include intravenous immunoglobulins (IVIG) and steroids. Prior studies …

Factors linked to severe outcomes in multisystem inflammatory syndrome in children (MIS-C) in the USA: a retrospective surveillance study

JY Abrams, ME Oster, SE Godfred-Cato… - The Lancet Child & …, 2021 - thelancet.com
Background Multisystem inflammatory syndrome in children (MIS-C) is a newly identified
and serious health condition associated with SARS-CoV-2 infection. Clinical manifestations …

Spectrum of severity of multisystem inflammatory syndrome in children: an EHR-based cohort study from the RECOVER program

S Rao, N Jing, X Liu, V Lorman, M Maltenfort… - Scientific reports, 2023 - nature.com
Multi-system inflammatory syndrome in children (MIS-C) is a severe post-acute sequela of
SARS-CoV-2 infection in children, and there is a critical need to unfold its highly …

[PDF][PDF] Treatment of multisystem inflammatory syndrome in children: understanding differences in results of comparative effectiveness studies

M Melgar, EG Seaby, AJ McArdle… - ACR Open …, 2022 - Wiley Online Library
Objective Two cohort studies in patients with multisystem inflammatory syndrome in children
(MIS‐C) demonstrated contrasting results regarding the benefit of initial immunomodulatory …

Impact of anakinra use on clinical outcomes in children with moderate or severe multisystem inflammatory syndrome in children: a propensity score matched …

EB Akkoyun, Z Most, H Katragadda, A Yu, L Nassi… - Pediatric …, 2023 - Springer
Background The treatment of children with multisystem inflammatory syndrome in children
(MIS-C) related to SARS-CoV-2 infection involves immunomodulatory therapies such as …

Case report: Exploring under the tip of the iceberg: A case series of “self-limiting” multisystem inflammatory syndrome in children

A Meneghel, G Martini, M Balzarin, N Zabadneh… - Frontiers in …, 2022 - frontiersin.org
Multisystem inflammatory syndrome in children (MIS-C) is a serious condition triggered by
SARS-COV-2 infection, characterized by persistent fever, multiorgan dysfunction, and …