Previous studies have shown that ATP and UTP are able to stimulate phospholipase C
(PLC) and proliferation in cultured aortic smooth muscle cells. Here we set out to …

It has previously been shown that ATP and UTP stimulate P2Y receptors in vascular smooth
muscle cells (VSMCs), but the nature of these receptors, in particular the contribution of …

Nucleotides regulate various effects including vascular tone. This study was aimed to
characterize P2Y receptors on endothelial cells of the aorta of C57BL6 mice. Five adjacent …

Mitogenic effects of the extracellular nucleotides ATP and UTP are mediated by P2Y1, P2Y2,
and P2Y4 receptors. However, it has not been possible to examine the highly expressed …

Background and purpose: The uracil nucleotides UDP and UTP have been reported to
activate P2Y2, P2Y4 and P2Y6 receptors to cause vasoconstriction. We have performed a …

Using a chick P2Y1 receptor cDNA probe we have isolated a mammalian P2Y receptor
clone from a bovine aortic endothelial cell Library. The sequence has a high degree of …

Studies using selective agonists have suggested that the contractile effect of extracellular
nucleotides, such as ATP and UTP, in blood vessels is mediated mainly by P2X1receptors …

Depending on the vascular bed considered, the actions of ATP on the endothelium are
mediated by either P2Y or P2U receptors. The two types of receptors seem to coexist on …

The actions of ATP and uridine 5′-triphosphate (UTP) were compared at P2X1 receptors in
acutely dissociated smooth muscles cells of the rat tail artery. ATP (30 nM–100 μM) and UTP …

The response of bovine aortic endothelial cells to adenosine 5'-triphosphate (ATP) is
mediated by both P2y and nucleotide/P2u receptors. In order to determine which form of the …