Low-dose albumin-coated gold nanorods induce intercellular gaps on vascular endothelium by causing the contraction of cytoskeletal actin
Z Li, J Liu, K Ballard, C Liang, C Wang - Journal of Colloid and Interface …, 2023 - Elsevier
Cytotoxicity of nanoparticles, typically evaluated by biochemical-based assays, often
overlook the cellular biophysical properties such as cell morphology and cytoskeletal actin …
overlook the cellular biophysical properties such as cell morphology and cytoskeletal actin …
Toxicity and cellular uptake of gold nanorods in vascular endothelium and smooth muscles of isolated rat blood vessel: importance of surface modification
Gold nanorods (GNRs) have promising applications in drug delivery and cancer treatment
and are generally administered via direct injection into the circulation. Thus it is necessary to …
and are generally administered via direct injection into the circulation. Thus it is necessary to …
Nanoparticle size-specific actin rearrangement and barrier dysfunction of endothelial cells
Y Liu, N Rogel, K Harada, L Jarett, CH Maiorana… - …, 2017 - Taylor & Francis
In this work, we evaluated the impact of gold nanoparticles on endothelial cell behavior and
function beyond the influence on cell viability. Five types of gold nanoparticles were studied …
function beyond the influence on cell viability. Five types of gold nanoparticles were studied …
Endothelial barrier dysfunction induced by nanoparticle exposure through actin remodeling via caveolae/raft-regulated calcium signalling
The rapid development of modern nanotechnology has resulted in nanomaterial being use
in nearly all applications of life, raising the potential risk of nanomaterial exposure alongside …
in nearly all applications of life, raising the potential risk of nanomaterial exposure alongside …
Correlating ligand density with cellular uptake of gold nanorods revealed by X-ray reflectivity
Ligands can endow unique physicochemical properties of nanomaterials and also mediate
biological effects of nanomaterials. It is unclear whether the ligand density affects cytotoxicity …
biological effects of nanomaterials. It is unclear whether the ligand density affects cytotoxicity …
In vitro effects of hollow gold nanoshells on human aortic endothelial cells
C Gu, H Wu, G Ge, X Li, Z Guo, Z Bian, J Xu… - Nanoscale Research …, 2016 - Springer
Gold nanoparticles are emerging as promising biomedical tools due to their unique
nanoscale characteristics. Our purpose was to synthesize a hollow-shaped gold …
nanoscale characteristics. Our purpose was to synthesize a hollow-shaped gold …
Cytotoxicity and cellular responses of gold nanorods to smooth muscle cells dependent on surface chemistry coupled action
Q Sun, X Shi, J Feng, Q Zhang, Z Ao, Y Ji, X Wu, D Liu… - Small, 2018 - Wiley Online Library
Gold nanorods (AuNRs), with their unique physicochemical properties, are recognized as
promising materials for biomedical applications. Chemical modification of their surfaces is …
promising materials for biomedical applications. Chemical modification of their surfaces is …
Polyvinylpyrrolidone-coated gold nanoparticles inhibit endothelial cell viability, proliferation, and ERK1/2 phosphorylation and reduce the magnitude of endothelial …
T Mohamed, S Matou-Nasri, A Farooq… - International journal …, 2017 - Taylor & Francis
Background Gold nanoparticles (AuNPs) demonstrate clinical potential for drug delivery and
imaging diagnostics. As AuNPs aggregate in physiological fluids, polymer-surface …
imaging diagnostics. As AuNPs aggregate in physiological fluids, polymer-surface …
Gold nanoparticles compromise TNF-α-induced endothelial cell adhesion molecule expression through NF-κB and protein degradation pathways and reduce …
The aim of this study was to investigate the anti-inflammatory effects and mechanism of
action of the gold nanoparticles (AuNPs) on vascular injury. In vitro vascular endothelial cell …
action of the gold nanoparticles (AuNPs) on vascular injury. In vitro vascular endothelial cell …
Dynamic protein corona of gold nanoparticles with an evolving morphology
A Nandakumar, W Wei, G Siddiqui… - … applied materials & …, 2021 - ACS Publications
Much has been learned about the protein coronae and their biological implications within
the context of nanomedicine and nanotoxicology. However, no data is available about the …
the context of nanomedicine and nanotoxicology. However, no data is available about the …
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