The role of astrocytes in neuronal function has received increasing recognition, but
disagreement remains about their function at the circuit level. Here we use in vivo two …

While neurons principally mediate brain function, astrocytes are emerging as cells with
important neuromodulatory actions in brain physiology. In addition to homeostatic roles …

Astrocytes seem to rely on relatively sluggish and spatially blurred Ca2+ waves to
communicate with fast and point-precise neural circuits. This apparent discrepancy could …

Key points In the brain, astrocytes detect neuronal activity and regulate neuronal excitability
and synaptic transmission. Recent studies show that calcium elevations that are localized …

Spontaneous neuronal activity is essential to neural development. Until recently, neurons
were believed to be the only excitable cells to display spontaneous activity. However …

Cumulative evidence supports bidirectional interactions between astrocytes and neurons,
suggesting glial involvement of neuronal information processing in the brain. Cytosolic …

The functional role of astrocyte calcium signaling in brain information processing was
intensely debated in recent decades. This interest was motivated by high resolution imaging …

Astrocytes exhibit spontaneous calcium fluctuations. These activities have not been
captured by large-scale recordings, and little is known about their collective dynamics. In situ …

An essential feature of neurons is their ability to centrally integrate information from their
dendrites. The activity of astrocytes, in contrast, has been described as mostly …

Elevation of intracellular Ca2+ in astrocytes can influence cerebral microcirculation and
modulate synaptic transmission. Recently, in vivo imaging studies identified delayed …