Characterisation of molecular mechanisms that control tumour invasion is a crucial step for
the identification of molecular markers to apply in cancer diagnosis and treatment. In this …

Abstract Background Inhibitor of DNA Binding 2 (ID2) plays a crucial role in tumor cell
proliferation, invasion, metastasis, and stemness. Aberrant ID2 expression is associated with …

The Id (i nhibitor of D NA binding) proteins are a family of helix-loop-helix (HLH) proteins
(Id1, Id2, Id3, and Id4) that lack the basic domain necessary for DNA binding. The Id1 protein …

Previous studies have reported that inhibitor of DNA binding 1 (ID1) exerts an oncogenic
role in a number of tumors. In the present study, the role of ID1 in the growth, invasion and …

BACKGROUND: The Id (inhibitor of DNA binding/differentiation) proteins belong to the helix-
loop-helix transcriptional regulatory factors, and play important roles in tumor development …

Inhibitor of DNA binding-1 (Id1) is a dominant-negative regulator of basic helix–loop–helix
transcription factor, which control malignant cell behaviors in several types of carcinomas …

Despite therapeutic advances, the prognosis of patients diagnosed with malignant glioma
has not improved in recent years. In particular, the molecular mechanisms that mediate …

The inhibitor of DNA binding (Id) proteins are regulators of cell cycle and cell differentiation.
Of all Id family proteins, Id1 is mostly linked to tumorigenesis, cellular senescence as well as …

Background The inhibitor of DNA-binding (ID) has been involved in cell cycle regulation,
apoptosis and angiogenesis. This prompted us to study ID functions in tumor advancement …

Inhibitor of DNA binding (ID) proteins are a class of helix-loop-helix (HLH) transcription
regulatory factors that act as dominant-negative antagonists of other basic HLH proteins …