Iron deficiency may exacerbate symptoms in the Restless Legs Syndrome (RLS). We
investigated the effect of intravenous iron sucrose or placebo on symptoms in patients with …

Background: Compromised iron status is important in restless legs syndrome
pathophysiology. We compared the efficacy and tolerability of ferric carboxymaltose (single …

OBJECTIVE: The aim of this study was to ascertain whether high-dose intravenous (IV) iron
sucrose could improve symptoms and change brain iron concentrations in idiopathic RLS …

Background and purpose: To evaluate the safety and efficacy of a single 1000 mg iron
infusion in treating Restless Legs Syndrome (RLS). Patients and methods: A single 1000 mg …

Background and purpose It is not clear which is preferred between iron supplement and a
dopamine agonist in the treatment of restless legs syndrome (RLS) with iron deficiency. The …

Background: Previous open-label trials have shown iron to be efficacious in the treatment of
restless legs syndrome. We performed a randomized, double-blind, placebo-controlled trial …

The impressive relief from restless legs syndrome (RLS) symptoms provided by levodopa
treatment indicates RLS is caused by a dopaminergic abnormality. But similar and more …

Reduced brain iron is strongly associated with restless legs syndrome (RLS). Oral iron
supplements are commonly recommended for RLS but are largely ineffective due to poor …

OBJECTIVE: To investigate the effect of intravenous (IV) iron (500mg ferric carboxymaltose
[FCM] as a single dose) on restless legs syndrome (RLS) severity on a day-to-day basis …

BACKGROUND: Various techniques used to assess brain iron concentrations have
demonstrated the presence of low iron stores in patients with restless legs syndrome (RLS) …