Infections due to the encapsulated fungus Cryptococcus neoformans are a significant cause
of morbidity and mortality in patients with impaired T-cell function, particularly those with …

Cryptococcus neoformans causes a life-threatening meningoencephalitis in a significant
percentage of AIDS patients. Mice immunized with a glycoconjugate vaccine composed of …

We synthesized Cryptococcus neoformans serotype A glucuronoxylomannan (GXM)
conjugate vaccines under conditions suitable for human use to prevent disseminated …

Cryptococcosis remains a significant cause of morbidity and mortality world-wide,
particularly among AIDS patients. Yet, to date, there are no licensed vaccines clinically …

Cryptosporidiosis, caused by Cryptosporidium parvum, is life‐threatening in individuals with
compromised immune systems and a common serious primary cause of outbreaks of …

Cryptococcus neoformans is an opportunistic fungal pathogen and the causative agent of
the disease cryptococcosis. Cryptococcosis is initiated as a pulmonary infection and in …

Abstract Defined Abs to the Cryptococcus neoformans capsular polysaccharide
glucuronoxylomannan (GXM) have been shown to be protective against experimental …

Antifungal therapy cannot eradicate Cryptococcus neoformans infections in
immunosuppressed patient groups. Therefore, adjunctive antibody-based therapy is being …

Cryptococcus neoformans is a fungus classified by the World Health Organization as a
critically important pathogen, which poses a significant threat to immunocompromised …

Cryptococcosis, a systemic mycosis that affects both the immunocompromised and
immunocompetent, is caused by the inhalation of dehydrated yeasts or fungal spores of …