Noninvasive analysis of volatile biomarkers in human emanations for health and early disease diagnosis

H Kataoka, K Saito, H Kato, K Masuda - Bioanalysis, 2013 - Taylor & Francis
Early disease diagnosis is crucial for human healthcare and successful therapy. Since any
changes in homeostatic balance can alter human emanations, the components of breath …

Sniffing out causes of gastrointestinal disorders: a review of volatile metabolomic biomarkers

I Ahmed, Z Niaz, F Ewbank, D Akarca… - Biomarkers in …, 2018 - Taylor & Francis
Distinct changes can be observed in the odor of human excretions during health and
disease. Identifying underlying volatile metabolites responsible for these odorous changes …

[HTML][HTML] High-quality identification of volatile organic compounds (VOCs) originating from breath

W Arulvasan, H Chou, J Greenwood, ML Ball, O Birch… - Metabolomics, 2024 - Springer
Abstract Introduction Volatile organic compounds (VOCs) can arise from underlying
metabolism and are detectable in exhaled breath, therefore offer a promising route to non …

Fecal volatile organic compounds: a novel, cheaper method of diagnosing inflammatory bowel disease?

CSJ Probert, S Reade, I Ahmed - Expert Review of Clinical …, 2014 - Taylor & Francis
The investigation of a novel, cheaper method of diagnosing inflammatory bowel disease
(IBD) is an area of active research. Recently, investigations into the metabolomic profile of …

Optimisation and validation of a HS-SPME–GC–IT/MS method for analysis of carbonyl volatile compounds as biomarkers in human urine: Application in a pilot study to …

I Calejo, N Moreira, AM Araújo, M Carvalho… - Talanta, 2016 - Elsevier
A new and simple analytical approach consisting of an automated headspace solid-phase
microextraction (HS-SPME) sampler coupled to gas chromatography-ion trap/mass …

[HTML][HTML] A headspace collection chamber for whole body volatilomics

S Rankin-Turner, CJ McMeniman - Analyst, 2022 - pubs.rsc.org
The human body secretes a complex blend of volatile organic compounds (VOCs) via the
skin, breath and bodily fluids, the study of which can provide valuable insight into the …

[HTML][HTML] The stool volatile metabolome of pre-term babies

A Frau, L Lett, R Slater, GR Young, CJ Stewart… - Molecules, 2021 - mdpi.com
The fecal metabolome in early life has seldom been studied. We investigated its evolution in
pre-term babies during their first weeks of life. Multiple (n= 152) stool samples were studied …

PTU-076 Diagnostic potential of volatile organic compounds as faecal biomarkers in inflammatory bowel disease

H Jayasena, T Khalid, CS Probert - Gut, 2013 - gut.bmj.com
Introduction VOCs can be utilised as non invasive biomarkers for gastrointestinal diseases
such as IBD, as changes in VOCs reflect internal metabolical and pathological processes …

[HTML][HTML] Monitoring type 2 diabetes from volatile faecal metabolome in Cushing's syndrome and single Afmid mouse models via a longitudinal study

C Lourenço, D Kelly, J Cantillon, M Cauchi, MA Yon… - Scientific reports, 2019 - nature.com
The analysis of volatile organic compounds (VOCs) as a non-invasive method for disease
monitoring, such as type 2 diabetes (T2D) has shown potential over the years although not …

Dual UHPLC-HRMS metabolomics and lipidomics and automated data processing workflow for comprehensive high-throughput gut phenotyping

P Vangeenderhuysen, J Van Arnhem… - Analytical …, 2023 - ACS Publications
In recent years, feces has surfaced as the matrix of choice for investigating the gut
microbiome-health axis because of its non-invasive sampling and the unique reflection it …