The scent of colorectal cancer: detection by volatile organic compound analysis

NKH de Boer, TGJ de Meij, FA Oort, IB Larbi… - Clinical …, 2014 - Elsevier
The overall metabolic state of an individual is reflected by emitted volatile organic
compounds (VOCs), which are gaseous carbon-based chemicals. In this review, we will …

Fecal volatile metabolomics predict gram-negative late-onset sepsis in preterm infants: a nationwide case-control study

NM Frerichs, S El Manouni El Hassani, N Deianova… - Microorganisms, 2023 - mdpi.com
Early detection of late-onset sepsis (LOS) in preterm infants is crucial since timely treatment
initiation is a key prognostic factor. We hypothesized that fecal volatile organic compounds …

[PDF][PDF] Volatile organic compounds (VOCs) found in urine and stool

B de Lacy Costello, NM Ratcliffe, A Amann… - … non-invasive diagnosis …, 2013 - academia.edu
VOC analysis of small molecules is a facile method for assessing stool and urine. Gut
chemistry is exceedingly complex and the results of VOC analysis offer a simplified picture of …

The human volatilome: volatile organic compounds (VOCs) in exhaled breath, skin emanations, urine, feces and saliva

A Amann, B de Lacy Costello, W Miekisch… - Journal of breath …, 2014 - iopscience.iop.org
Breath analysis is a young field of research with its roots in antiquity. Antoine Lavoisier
discovered carbon dioxide in exhaled breath during the period 1777–1783, Wilhelm (Vilém) …

Simultaneous analysis of 28 urinary VOC metabolites using ultra high performance liquid chromatography coupled with electrospray ionization tandem mass …

KU Alwis, BC Blount, AS Britt, D Patel, DL Ashley - Analytica chimica acta, 2012 - Elsevier
Volatile organic compounds (VOCs) are ubiquitous in the environment, originating from
many different natural and anthropogenic sources, including tobacco smoke. Long-term …

Rapid analysis of volatile fatty acids in feces by headspace gas chromatography tandem mass spectrometry

Z Jiang, Y Wang, R Chen, Y Zhu… - Chinese Journal of …, 2014 - pesquisa.bvsalud.org
ABSTRACT A rapid headspace gas chromatography tandem mass spectrometric (HS-
GC/MS) method was established for the analysis of volatile fatty acids (VFAs) in the feces …

Simultaneous assessment of urinary and fecal volatile organic compound analysis in de novo pediatric IBD

S el Manouni el Hassani, S Bosch, JPM Lemmen… - Sensors, 2019 - mdpi.com
Endoscopic evaluation is mandatory in establishing the diagnosis of pediatric inflammatory
bowel disease (IBD), but unfortunately carries a high burden on patients. Volatile organic …

Sample preparation and recent trends in volatolomics for diagnosing gastrointestinal diseases

T Majchrzak, W Wojnowski, G Piotrowicz… - TrAC Trends in …, 2018 - Elsevier
The analysis of the human volatilome can be successfully used for rapid and non-invasive
diagnostics of gastrointestinal diseases. However, the introduction of techniques based on …

Optimization of the quantitative protocol for organic acid in fecal samples using gas chromatography-mass spectrometry

Y Wang, L Li, M Zhang, R Feng, L Liu - Journal of Pharmaceutical and …, 2024 - Elsevier
Organic acids (OAs) play important roles in a variety of intracellular metabolic pathways,
such as the tricarboxylic acid cycle, fatty acid oxidation, glycolysis. The accurate detection of …

Metabolomic analysis—Addressing NMR and LC-MS related problems in human feces sample preparation

S Moosmang, M Pitscheider, S Sturm, C Seger… - Clinica Chimica …, 2019 - Elsevier
Metabolomics is a well-established field in fundamental clinical research with applications in
different human body fluids. However, metabolomic investigations in feces are currently an …